Allergen-specific immunotherapy: Carrots and sticks for the...
09. June 2017 The active substance Tofacitinib facilitates hyposensitization in the treatment of allergic asthma. This discovery was made by scientists at the Center of Allergy and Environment (ZAUM), a joint research institution of the Helmholtz Zentrum München and the Technical University of Munich (TUM). The findings of their research have now been published in the PLOS ONE Journal.People who suffer from...read more
ERC Starting Grant for allergy research in the gut
01. June 2017 The European Research Council (ERC) will be funding the ALLERGUT project at the Helmholtz Zentrum München for the next five years with an ERC Starting Grant. Working in this framework, the researchers headed by Dr. Caspar Ohnmacht want to discover if and how bacteria in the intestines can assist or prevent the development of allergies. The total funding amounts to 1.5 million euros. It is...read more
Immunotherapy against bee stings in some cases incomplete
16. May 2017 The preparations that are used for allergen immunotherapy against bee sting allergies do not always contain all the relevant venom components. This was the conclusion of an examination conducted by allergy experts at the Helmholtz Zentrum München and the Technical University of Munich (TUM). According to their report in ‘Human Vaccines and Immunotherapeutics’, this could possibly influence the...read more
First world-wide interactive pollen station map
10. May 2017 ZAUM is proud to announce the first interactive map showing all available pollen monitoring stations in the world.read more
Cytochrome P450s – metabolic keys in immunity
30. March 2017 Cytochrome P450 enzymes (CYPs) oxidize lipophilic molecules and are well examined in the liver and environmentally exposed tissues. Renate Effner (research group Environment, Prof. Dr. Jeroen T. Buters) now reported that CYP1 enzymes are cleaners of the aryl hydrocarbon receptor (AHR) in human immune cells, thereby limiting the effects of ligands. The findings, which were elaborated in...read more
ZAUM on TV
29. March 2017 The public awareness about allergic diseases and the allergic march are rising. Several TV formats gave Prof. Carsten Schmidt-Weber and Prof. Jeroen Buters from the Center of Allergy and Environment (ZAUM) the chance to speak about allergy and pollen monitoring to clarify interesting facts and future perspectives:Pollen-Network on BR MediathekBR Abendschau (starting at minute 7)ARD W wie...read more
UNITED ACTION FOR ALLERGY AND ASTHMA
28. March 2017 This year, the European Academy of Allergy and Clinical Immunology (EAACI) and the European Federation of Allergy and Airways Diseases Patients Associations (EFA) are initiating a Political Call to Action, targeted at EU and national policymakers, to act on Allergy and Asthma in Europe.The Call to Action is embedded in the context of the European Parliament Interest Group on Allergy and Asthma...read more
Is an agent used to treat psoriasis aimed at the wrong target?
29. November 2016 Neuherberg, November 2016: The antibody ustekinumab is in use for treatment of psoriasis since 2009. It inhibits the underlying inflammation by neutralizing certain messengers of the immune system. Researchers at the Helmholtz Zentrum München, the Technical University of Munich and the University of Zurich have now shown in ‘Nature Communications’ that one of these messengers could...read more
Response to House Dust Mites is Age-Dependent
29. August 2016 Neuherberg, August 2016: Adults suffering from a house dust mite allergy, exhibit a cascade of inflammatory signals on the surface of their airways, which leads to airway remodeling. This process cannot be influenced by standard cortisone therapy. In an experimental model researchers around Dr. Julia Esser-von Bieren (research group Immunemodulation) have reported that Wnt5a, the enzymes...read more
Recombinant antigen 5 from seven hymenoptera species in diagnosis
12. August 2016 Neuherberg, August 2016: Stings of hymenoptera can cause severe anaphylaxis in untreated venom-allergic patients. A correct diagnosis regarding the relevant species for immunotherapy is often hampered by clinically irrelevant cross-reactivity. Maximilian Schiener in the group of Dr. Simon Blank (Molecular and Translational Allergology) could show that the application of recombinant produced...read more
Prof. Carsten Schmidt-Weber on air at the SWR2 Forum
05. July 2016 Prof. Carsten Schmidt-Weber, Head of the Center of Allergy and Environment (ZAUM), took part in the discussion about "Allergies - do we trivialize the risks of this widespread disease?" at the SWR2 Forum. read more
Molecular Allergology User's Guide
27. June 2016 Vienna, June 2016: The ZAUM (Dr. Simon Blank; Molecular and Translational Allergology group) contributed to the establishment of the world’s first comprehensive handbook on Molecular Allergology. The book of more than 300 pages, named “Molecular Allergology User's Guide”, was officially presented to the scientific and medical community at the congress of the European Academy of Allergy and...read more
Several prizes for ZAUM members at the EAACI 2016 Congress in...
27. June 2016 Vienna, June 2016: Several members of ZAUM successfully participated in the annual congress of the European Academy of Allergy and Clinical Immunology (EAACI): Dennis Rußkamp, Constanze Jakwerth, Ulrich Zissler and Julia Esser-von Bieren won scholarships for presenting their work in the oral abstract sessions. read more
Review on "Tolerance to the Intestinal Microbiota Mediated by...
31. May 2016 Neuherberg, May 2016: Harmless microbes colonizing the gut require the establishment of a well-equilibrated symbiosis between this microbiota and its host. A recent review summarizes novel insights into how this microbiota is tolerized by the immune system.read more
Development of a component-resolved approach to enhance...
31. May 2016 Neuherberg/Munich/Luxembourg, February 2016: Researchers from the ZAUM (Dr. Blank, Prof. Schmidt-Weber) in cooperation with the Luxembourg Institute of Health (Prof. Ollert) and the Clinic of Dermatology and Allergy of the Technical University of Munich developed a component-resolved approach to enhance diagnostic accuracy in patients with mastocytosis and hymenoptera venom allergy.read more
Stefanie Eyerich received the Henning Løwenstein Research Award
26. November 2015 Rome/Neuherberg, November 2015: Stefanie Eyerich was awarded the WAO Henning Loøwenstein Research Award (20.000 €) for her achievements in the field of allergy research. Stefanie Eyerich, who is working at the Center of Allergy and Environment (ZAUM) received the price at a solemn award ceremony in Rome on the 20th of November.read more
Poster Prize for Dennis Rußkamp and Maximilian Schiener
15. October 2015 Deutscher Allergie Kongress 2015, Cologne and EAACI Congress 2015, Barcelona.read more
The role of the microbiota in preventing allergies
10. July 2015 Neuherberg & Paris, July 2015: The human body is inhabited by billions of symbiotic bacteria, carrying a diversity that is unique to each individual. The microbiota is involved in many mechanisms, including digestion, vitamin synthesis and host defense. It is well established that a loss of bacterial symbionts promotes the development of allergies. Scientists at Helmholtz Zentrum Munich, at the...read more
"Es gibt nur zwei Schutzmöglichkeiten"
16. March 2015 München, 16.03.2015. Interview mit Herrn Prof. Buters mit dem Bayerischen Rundfunk. Am Montag wurde ein Interview von Bayern2 ausgestrahlt, in dem unser Allergie-Experte Heroen Buters (TU München) zu dem Thema Stellung bezieht. Die Anfälligkeit für Heuschnupfen verdoppelt sich von Dekade zu Dekade, trotz der angebotenen Schutzmaßnahmen wie der Hypersensibilisierung.
New diagnostic test to distinguish psoriasis from eczema
10. July 2014Neuherberg, 10 July 2014. In many patients it is not easy to differentiate between the chronic inflammatory skin diseases psoriasis and eczema. Researchers at the Helmholtz Zentrum München and the Technical University of Munich (TUM) have now developed a procedure based on a skin analysis that enables an exact diagnosis to be made. The results have been published in the specialist journal Science...read more
Oberfläche von Nanopartikeln steuert gesundheitliche Effekte
08. July 2014Neuherberg, 08.07.2014. Nanopartikel können eine Rolle bei der Entstehung allergischer Reaktionen spielen. Durch bestimmte chemische Veränderungen ihrer Oberfläche allerdings lässt sich dieser Effekt reduzieren. Dies haben Wissenschaftler um PD. Dr. Francesca Alessandrini vom Institut für Allergieforschung (IAF) am Helmholtz Zentrum München in einer aktuellen Studie herausgefunden, die im...read more
High Ambient Ozone Levels Lead to More Allergenic Birch Pollen
06. December 2013Neuherberg, 06.12.2013. Scientists of Helmholtz Zentrum München, together with their colleagues at Technische Universität München, have discovered that ozone is a key factor in the association between climate change, urbanization and the increasing prevalence of allergic diseases and symptoms. The results of the studies clearly suggest that an increase in allergic diseases can be expected.read more
Head
Prof. Dr. rer. nat. Carsten B. Schmidt-Weber
Chair for Molecular Allergology (Klinikum rechts der Isar)
Director of the Institute of Allergy research (IAF; Helmholtz Zentrum München)
Contact
Zentrum Allergie und Umwelt (ZAUM)
Technische Universität und Helmholtz Zentrum München
Libuse Pilz (Sekretariat)
Biedersteiner Str. 29
80802 München
Germany
Phone: +49 89 4140-3451
Fax +49 89 4140-3452
E-Mail: zaum@tum.de