Published in the American Journal of Respiratory and Critical Care Medicine, the study shows that the risk allele boosts GSDMB expression, leading to inflammation and a weakened antiviral response. The researchers analyzed nasal samples from 261 children, revealing a potential mechanism behind virus-triggered asthma. These insights open the door for targeted therapies aimed at modulating GSDMB, offering hope for preventing asthma in genetically predisposed children.