Simon Blank and Maximilian Schiener (Group Molecular and Translational Allergology)

Neuherberg, August 2016: Stings of hymenoptera can cause severe anaphylaxis in untreated venom-allergic patients. A correct diagnosis regarding the relevant species for immunotherapy is often hampered by clinically irrelevant cross-reactivity. Maximilian Schiener in the group of Dr. Simon Blank (Molecular and Translational Allergology) could show that the application of recombinant produced antigen 5 of different Hymenoptera species in sIgE measurements together with basophil-activation tests (Prof. Dr. Eberlein, Department of Dermatology and Allergy Biederstein, Technical University of Munich) allows the individual dissection of clinically relevant sensitization.
Application of recombinant antigen 5 allergens from 7 allergy-relevant Hymenoptera species in diagnostics, doi 10.1111/all.13000, Original Publication

NEWS: Prof. Carsten Schmidt-Weber on air at the SWR2 Forum

Prof. Carsten Schmidt-Weber, Head of the Center of Allergy and Environment

Munich, July 2016: Prof. Carsten Schmidt-Weber, Head of the Center of Allergy and Environment (ZAUM), took part in the discussion about "Allergies  - do we trivialize the risks of this widespread disease?" at the SWR2 Forum. The moderator Susanne Kaufmann, Prof. Dr. Carsten Schmidt-Weber, the medicinal journalist Dr. Dietlinde Burkhardt and Prof. Dr. Roland Buhl, Head of the Focus Pneumology at the University Clinic Mainz, are disucssing about the topic, listen to the discussion round in German.

NEWS: “Molecular Allergology User's Guide”

Cover image of the Molecular Allergology User's Guide, published by the European Academy for Allergy and Clinical Immunology (EAACI)

Vienna, June 2016: The ZAUM (Dr. Simon Blank; Molecular and Translational Allergology group) contributed to the establishment of the world’s first comprehensive handbook on Molecular Allergology. The book of more than 300 pages, named “Molecular Allergology User's Guide”, was officially presented to the scientific and medical community at the congress of the European Academy of Allergy and Clinical Immunology (EAACI) in Vienna in June. The handbook represents a straightforward guide that describes the new developments in molecular allergology and that provides the basis for a refined, earlier diagnosis of the allergic reactions and ultimately for a tailored individualized management of the patients. The handbook can be downloaded and, moreover, was published as a supplement in the Journal Pediatric Allergy and Immunology (Pediatr Allergy Immunol. 2016 May;27 Suppl 23:1-250).

News: Several prizes for ZAUM members at the EAACI 2016 Congress in Vienna

Vienna, June 2016: Several members of ZAUM successfully participated in the annual congress of the European Academy of Allergy and Clinical Immunology (EAACI): Dennis Rußkamp, Constanze Jakwerth, Ulrich Zissler and Julia Esser-von Bieren won scholarships for presenting their work in the oral abstract sessions. In addition, Julia Esser-von Bieren won two abstract prizes (poster and oral) for presenting her work on “Age dependent regulation of remodeling factors”. She was also the first woman to cross the finish line in this year’s “Beat Allergy” run, a sportive event during the EAACI Congress to raise funding and awareness for allergy research.

NEWS: Review on "Tolerance to the Intestinal Microbiota Mediated by ROR(yt)+ cells"

Dr. Caspar Ohnmacht
(ZAUM, TU and Helmholtz Zentrum Munich)

Neuherberg, May 2016: Harmless microbes colonizing the gut require the establishment of a well-equilibrated symbiosis between this microbiota and its host. A recent review summarizes novel insights into how this microbiota is tolerized by the immune system. Particularly, cells expressing the transcription factor RAR-related orphan-like γt [ROR(γt)] seem to control such tolerogenic mechanisms in both the innate and adaptive immune system.


NEWS: Development of a component-resolved approach to enhance diagnostic accuracy

Dr. Simon Blank (ZAUM, TU and Helmholtz Zentrum Munich), Prof. Dr. Markus Ollert (Luxembourg Institute of Health)

Neuherberg/Munich/Luxembourg, February 2016: Researchers from the ZAUM (Dr. Blank, Prof. Schmidt-Weber) in cooperation with the Luxembourg Institute of Health (Prof. Ollert) and the Clinic of Dermatology and Allergy of the Technical University of Munich developed a component-resolved approach to enhance diagnostic accuracy in patients with mastocytosis and hymenoptera venom allergy. The work by Michel et al., ...


NEWS: Stefanie Eyerich received the Henning Løwenstein Research Award

Henning Løwenstein (ALK-Abelló GmbH), Awardee Stefanie Eyerich and Lanny Rosenwasser (President of the World Allergy Organization - WAO), Source: ALK-Abelló GmbH

Rome/Neuherberg, November 2015: Stefanie Eyerich was awarded the WAO Henning Loøwenstein Research Award (20.000 €) for her achievements in the field of allergy research. Stefanie Eyerich, who is working at the Center of Allergy and Environment (ZAUM) received the price at a solemn award ceremony in Rome on the 20th of November.
In her working group „Skin Immunology and Allergy“ she is focusing on the role of T helper cells in the context of skin allergic diseases like e.g. atopic dermatitis. The group is currently working on two approaches:
On the one hand side Eyerich...

Source: press releases, Helmholtz Center Munich

NEWS: The role of the microbiota in preventing allergies

The intestinal microbiota is significantly influencing the immune system of the host. Source: Dr. Caspar Ohnmacht, ZAUM

Neuherberg & Paris, July 2015: The human body is inhabited by billions of symbiotic bacteria, carrying a diversity that is unique to each individual. The microbiota is involved in many mechanisms, including digestion, vitamin synthesis and host defense. It is well established that a loss of bacterial symbionts promotes the development of allergies. Scientists at Helmholtz Zentrum Munich, at the Technical University of Munich (TUM), and the Institut Pasteur in Paris have succeeded in explaining this phenomenon, and demonstrate how the microbiota acts on the balance of the immune system: the presence of microbes specifically blocks the immune cells responsible for triggering allergies. These results are published in the journal Science.
Ohnmacht, C. et al. (2015). The microbiota regulates type 2 immunity through RORgt+ T cells, Science, DOI: 10.1126/science.aac4263

Source: press releases, Helmholtz Center Munich


Zentrum Allergie und Umwelt (ZAUM)
Technische Universität und Helmholtz Zentrum München

Biedersteiner Str. 29
80802 München

Phone: +49 89 4140 3451
Fax +49 89 4140 3452




Prof. Carsten B. Schmidt-Weber, PhD
Chair for Molecular Allergology (Klinikum rechts der Isar)
Director of the Institute of Allergy research (IAF; Helmholtz Zentrum München)
Head of the Munich Allergy Research Centers (MARC)


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