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IgA+ memory B-cells are significantly increased in patients with asthma and small airway dysfunction.

Habener A, Grychtol R, Gaedcke S, DeLuca D, Dittrich AM, Happle C, Abdo M, Watz H, Pedersen F, König IR, Thiele D, Kopp MV, von Mutius E, Bahmer T, Rabe KF, Meyer-Bahlburg A, Hansen G, ALLIANCE Study Group as part of the German Center for Lung Research (DZL), Fuchs O, Roesler B, Welchering N, Kohistani-Greif N, Kurz J, Landgraf-Rauf K, Laubhahn K, Maison N, Liebl C, Schaub B, Ege M, Illi S, Hose A, Zeitlmann E, Berbig M, Marzi C, Schauberger C, Zissler U, Schmidt-Weber C, Ricklefs I, Diekmann G, Liboschik L, Voigt G, Sultansei L, Weckmann M, Nissen G, Kirsten AM, Waschki B, Herzmann C, Biller H, Gaede KI, Bovermann X, Steinmetz A, Husstedt BL, Nitsche C, Veith V, Szewczyk M, Brinkmann F, Malik A, Schwerk N, Dopfer C, Price M, Jirmo AC, Liu B, Calveron MR, Weber S, Foth S, Skevaki C, Renz H, Meyer M, Schildberg T, Rietschel E, van Koningsbruggen-Rietschel S, Alcazar M 

Eur Respir J, 2022; 60(5)

 

Alternaria spore exposure in Bavaria, Germany, measured using artificial intelligence algorithms in a network of BAA500 automatic pollen monitors.

González-Alonso M, Boldeanu M, Koritnik T, Gonçalves J, Belzner L, Stemmler T, Gebauer R, Grewling Ł, Tummon F, Maya-Manzano JM, Ariño AH, Schmidt-Weber C, Buters J 

Sci Total Environ, 2022; 861

 

Towards European automatic bioaerosol monitoring: Comparison of 9 automatic pollen observational instruments with classic Hirst-type traps.

Maya-Manzano JM, Tummon F, Abt R, Allan N, Bunderson L, Clot B, Crouzy B, Daunys G, Erb S, Gonzalez-Alonso M, Graf E, Grewling Ł, Haus J, Kadantsev E, Kawashima S, Martinez-Bracero M, Matavulj P, Mills S, Niederberger E, Lieberherr G, Lucas RW, O'Connor DJ, Oteros J, Palamarchuk J, Pope FD, Rojo J, Šaulienė I, Schäfer S, Schmidt-Weber CB, Schnitzler M, Šikoparija B, Skjøth CA, Sofiev M, Stemmler T, Triviño M, Zeder Y, Buters J

Sci Total Environ, 2022; 866

 

Molecular determination of insect venom allergies.

Blank S, Jakwerth CA, Zissler UM, Schmidt-Weber CB 

Expert Rev Mol Diagn, 2022; 22(11):983-986

 

Trained immunity in type 2 immune responses.

Hartung F, Esser-von Bieren J 

Mucosal Immunol, 2022; 15(6):1158-1169

 

Impact of Volatile and Semi-volatile Organic Compounds from Farming Environments on Allergy-Related Cellular Processes

Gawlitta N, Zimmermann EJ, Orasche J, Huber A, Buters J, Di Bucchianico S, Oeder S, Groeger T, Zimmermann R 

Expo. Health, 2022; 14(1):185-201

 

Acetate, a metabolic product of Heligmosomoides polygyrus, facilitates intestinal epithelial barrier breakdown in a FFAR2-dependent manner.

Schälter F, Frech M, Dürholz K, Lucas S, Sarter K, Lebon L, Esser-von Bieren J, Dubey LK, Voehringer D, Schett G, Harris NL, Zaiss MM 

Int J Parasitol, 2022; 52(9):591-601

 

β-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trapping.

Bouchery T, Volpe B, Doolan R, Coakley G, Moyat M, Esser-von Bieren J, Wickramasinghe LC, Hibbs ML, Sotillo J, Camberis M, Le Gros G, Khan N, Williams D, Harris NL 

Immunol Cell Biol, 2022; 100(4):223-234

 

Diversity of T Helper and Regulatory T Cells and Their Contribution to the Pathogenesis of Allergic Diseases.

Ohnmacht C, Eyerich S 

Handb Exp Pharmacol, 2022; 268:265-296

 

Erfolgreiche Therapie einer akuten generalisierten pustulösen Psoriasis mit dem IL-23p19-Antikörper Risankizumab.

Heyer S, Seiringer P, Eyerich S, Pilz AC, Steimle-Grauer SA, Eyerich K, Biedermann T, Böhner A 

J Dtsch Dermatol Ges, 2022; 20(10):1362-1364

 

Spatial transcriptomics landscape of lesions from non-communicable inflammatory skin diseases.

Schäbitz A, Hillig C, Mubarak M, Jargosch M, Farnoud A, Scala E, Kurzen N, Pilz AC, Bhalla N, Thomas J, Stahle M, Biedermann T, Schmidt-Weber CB, Theis F, Garzorz-Stark N, Eyerich K, Menden MP, Eyerich S 

Nat Commun, 2022; 13(1)

 

Monitoring disease activity of pollen allergies: What crowdsourced data are telling us.

J Schober A, Tizek L, Johansson EK, Ekebom A, Wallin JE, Buters J, Schneider S, Zink A

World Allergy Organ J, 2022; 15(12)

 

Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice.

Musiol S, Harris CP, Karlina R, Gostner JM, Rathkolb B, Schnautz B, Schneider E, Mair L, Vergara EE, Flexeder C, Koletzko S, Bauer CP, Schikowski T, Berdel D, von Berg A, Herberth G, Rozman J, Hrabe de Angelis M, Standl M, Schmidt-Weber CB, Ussar S, Alessandrini F 

Allergy, 2022; online ahead of print

 

In vitro neutrophil migration is associated with inhaled corticosteroid treatment and serum cytokines in pediatric asthma.

Lemmel S, Weckmann M, Wohlers A, Jirmo AC, Grychtol R, Ricklefs I, Nissen G, Bachmann A, Singh S, Caicedo J, Bahmer T, Hansen G, Von Mutius E, Rabe KF, Fuchs O, Dittrich AM, Schaub B, Happle C, Carpenter AE, Kopp MV, Becker T, ALLIANCE Study Group as part of the German Centre for Lung Research (DZL)  

Front Pharmacol, 2022; 13

 

Role of microRNAs in type 2 diseases and allergen-specific immunotherapy.

Jakwerth CA, Kitzberger H, Pogorelov D, Müller A, Blank S, Schmidt-Weber CB, Zissler UM 

Front Allergy, 2022; 3

 

A comprehensive aerobiological study of the airborne pollen in the Irish environment.

Markey E, Clancy JH, Martínez-Bracero M, Maya-Manzano JM, Smith M, Skjøth C, Dowding P, Sarda-Estève R, Baisnée D, Donnelly A, McGillicuddy E, Sewell G, O'Connor DJ 

Aerobiologia (Bologna), 2022; 38(3):343-366

 

Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.

Xie K, Fuchs H, Scifo E, Liu D, Aziz A, Aguilar-Pimentel JA, Amarie OV, Becker L, da Silva-Buttkus P, Calzada-Wack J, Cho YL, Deng Y, Edwards AC, Garrett L, Georgopoulou C, Gerlini R, Hölter SM, Klein-Rodewald T, Kramer M, Leuchtenberger S, Lountzi D, Mayer-Kuckuk P, Nover LL, Oestereicher MA, Overkott C, Pearson BL, Rathkolb B, Rozman J, Russ J, Schaaf K, Spielmann N, Sanz-Moreno A, Stoeger C, Treise I, Bano D, Busch DH, Graw J, Klingenspor M, Klopstock T, Mock BA, Salomoni P, Schmidt-Weber C, Weiergräber M, Wolf E, Wurst W, Gailus-Durner V, Breteler MMB, Hrabě de Angelis M, Ehninger D 

Nat Commun, 2022; 13(1)

 

Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death.

Frank D, Garnish SE, Sandow JJ, Weir A, Liu L, Clayer E, Meza L, Rashidi M, Cobbold SA, Scutts SR, Doerflinger M, Anderton H, Lawlor KE, Lalaoui N, Kueh AJ, Eng VV, Ambrose RL, Herold MJ, Samson AL, Feltham R, Murphy JM, Ebert G, Pearson JS, Vince JE 

iScience, 2022; 25(7)

 

Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling.

Dietschmann A, Schruefer S, Westermann S, Henkel F, Castiglione K, Willebrand R, Adam J, Ruland J, Lang R, Sheppard DC, Esser-von-Bieren J, Radtke D, Krappmann S, Voehringer D 

mBio, 2022; 13(4)

 

Mast Cell Activation Syndromes: Collegium Internationale Allergologicum Update 2022.

Valent P, Hartmann K, Bonadonna P, Niedoszytko M, Triggiani M, Arock M, Brockow K 

Int Arch Allergy Immunol, 2022; 183(7):693-705

 

Tissue Niches Formed by Intestinal Mesenchymal Stromal Cells in Mucosal Homeostasis and Immunity.

Pasztoi M, Ohnmacht C 

Int J Mol Sci, 2022; 23(9)

 

Helminthic dehydrogenase drives PGE2 and IL-10 production in monocytes to potentiate Treg induction.

Prodjinotho UF, Gres V, Henkel F, Lacorcia M, Dandl R, Haslbeck M, Schmidt V, Winkler AS, Sikasunge C, Jakobsson PJ, Henneke P, Esser-von Bieren J, Prazeres da Costa C 

EMBO Rep, 2022; 23(5)

 

Bronchial inflammation biomarker patterns link humoral immunodeficiency with bronchiectasis-related small airway dysfunction.

Zissler UM, Thron A, Eckrich J, Bakhtiar S, Schubert R, Zielen S 

Clin Exp Allergy, 2022; 52(6):760-773

 

NF-κB in control of regulatory T cell development, identity, and function.

Hövelmeyer N, Schmidt-Supprian M, Ohnmacht C 

J Mol Med, 2022; 100(7):985-995

 

ZC3H12C expression in dendritic cells is necessary to prevent lymphadenopathy of skin-draining lymph nodes.

Clayer E, Frank D, Anderton H, Zhang S, Kueh A, Heim V, Nutt SL, Chopin M, Bouillet P 

Immunol Cell Biol, 2022; 100(3):160-173

 

α-Gal present on both glycolipids and glycoproteins contributes to immune response in meat-allergic patients.

Chakrapani N, Fischer J, Swiontek K, Codreanu-Morel F, Hannachi F, Morisset M, Mugemana C, Bulaev D, Blank S, Bindslev-Jensen C, Biedermann T, Ollert M, Hilger C 

J Allergy Clin Immunol,2022; 150(2):396-405.e11

 

Not just "leuko" after all: Epithelial leukotriene production in type 2 immunity.

Henkel FDR, Bieren JE 

Sci Immunol, 2022; 7(67)

 

Effect of air filtration on house dust mite, cat and dog allergens and particulate matter in homes.

Maya-Manzano JM, Pusch G, Ebner von Eschenbach C, Bartusel E, Belzner T, Karg E, Bardolatzy U, Scheja M, Schmidt-Weber C, Buters J 

Clin Transl Allergy, 2022; 12(4)

 

Ex Vivo Immunomodulatory Effects of Lactobacillus-, Lacticaseibacillus-, and Bifidobacterium-Containing Synbiotics on Human Peripheral Blood Mononuclear Cells and Monocyte-Derived Dendritic Cells in the Context of Grass Pollen Allergy.

Heldner A, Heath MD, Schnautz B, Kotz S, Chaker A, Kramer MF, Jakwerth CA, Zissler UM, Schmidt-Weber CB, Blank S 

Probiotics Antimicrob Proteins, 2022; online ahead of print

 

Allergen Content of Therapeutic Preparations for Allergen-Specific Immunotherapy of European Paper Wasp Venom Allergy.

Grosch J, Lesur A, Kler S, Bernardin F, Dittmar G, Francescato E, Hewings SJ, Jakwerth CA, Zissler UM, Heath MD, Ollert M, Kramer MF, Hilger C, Bilò MB, Schmidt-Weber CB, Blank S 

Toxins (Basel), 2022; 14(4)

 

Thermosensitive PLGA-PEG-PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy.

Heine S, Aguilar-Pimentel A, Russkamp D, Alessandrini F, Gailus-Durner V, Fuchs H, Ollert M, Bredehorst R, Ohnmacht C, Zissler UM, Hrabě de Angelis M, Schmidt-Weber CB, Blank S 

Pharmaceutics, 2022; 14(8)

 

Macrophages acquire a TNF-dependent inflammatory memory in allergic asthma.

Lechner A, Henkel FDR, Hartung F, Bohnacker S, Alessandrini F, Gubernatorova EO, Drutskaya MS, Angioni C, Schreiber Y, Haimerl P, Ge Y, Thomas D, Kabat AM, Pearce EJ, Ohnmacht C, Nedospasov SA, Murray PJ, Chaker AM, Schmidt-Weber CB, Esser-von Bieren J 

J Allergy Clin Immunol, 2022; 149(6):2078-2090

 

Role of Respiratory Epithelial Cells in Allergic Diseases.

Jakwerth CA, Ordovas-Montanes J, Blank S, Schmidt-Weber CB, Zissler UM 

Cells, 2022; 11(9)

 

ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion.

Jocher G, Grass V, Tschirner SK, Riepler L, Breimann S, Kaya T, Oelsner M, Hamad MS, Hofmann LI, Blobel CP, Schmidt-Weber CB, Gokce O, Jakwerth CA, Trimpert J, Kimpel J, Pichlmair A, Lichtenthaler SF 

EMBO Rep, 2022; 23(6)

 

Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages.

Bohnacker S, Hartung F, Henkel F, Quaranta A, Kolmert J, Priller A, Ud-Dean M, Giglberger J, Kugler LM, Pechtold L, Yazici S, Lechner A, Erber J, Protzer U, Lingor P, Knolle P, Chaker AM, Schmidt-Weber CB, Wheelock CE, Esser-von Bieren J 

Mucosal Immunol, 2022; 15(3):515-524

 

Correction to: Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages.

Bohnacker S, Hartung F, Henkel F, Quaranta A, Kolmert J, Priller A, Ud-Dean M, Giglberger J, Kugler LM, Pechtold L, Yazici S, Lechner A, Erber J, Protzer U, Lingor P, Knolle P, Chaker AM, Schmidt-Weber CB, Wheelock CE, Esser-von Bieren J 

Mucosal Immunol, 2022; 15(4):798-798

 

Immunocompromised Patients with Therapy-Refractory Chronic Skin Diseases Show Reactivation of Latent Epstein‒Barr Virus and Cytomegalovirus Infection.

Speth P, Jargosch M, Seiringer P, Schwamborn K, Bauer T, Scheerer C, Protzer U, Schmidt-Weber C, Biedermann T, Eyerich S, Garzorz-Stark N 

J Invest Dermatol, 2022; 142(3 Pt A):549-558.e6

 

Lung Epithelial CYP1 Activity Regulates Aryl Hydrocarbon Receptor Dependent Allergic Airway Inflammation.

Alessandrini F, de Jong R, Wimmer M, Maier AM, Fernandez I, Hils M, Buters JT, Biedermann T, Zissler UM, Hoffmann C, Esser-von-Bieren J, Schmidt-Weber CB, Ohnmacht C 

Front Immunol, 2022; 13

 

A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria.

Kreft L, Schepers A, Hils M, Swiontek K, Flatley A, Janowski R, Mirzaei MK, Dittmar M, Chakrapani N, Desai MS, Eyerich S, Deng L, Niessing D, Fischer K, Feederle R, Blank S, Schmidt-Weber CB, Hilger C, Biedermann T, Ohnmacht C 

Front Immunol, 2022; 13

 

Differential effects of lung inflammation on insulin resistance in humans and mice.

Karlina R, Flexeder C, Musiol S, Bhattacharyya M, Schneider E, Altun I, Gschwendtner S, Neumann AU, Nano J, Schloter M, Peters A, Schulz H, Schmidt-Weber CB, Standl M, Traidl-Hoffmann C, Alessandrini F, Ussar S

Allergy, 2022; 77(8):2482-2497

 

Early reduction of SARS-CoV-2-replication in bronchial epithelium by kinin B2 receptor antagonism.

Jakwerth CA, Feuerherd M, Guerth FM, Oelsner M, Schellhammer L, Giglberger J, Pechtold L, Jerin C, Kugler L, Mogler C, Haller B, Erb A, Wollenberg B, Spinner CD, Buch T, Protzer U, Schmidt-Weber CB, Zissler UM, Chaker AM 

J Mol Med, 2022; 100 (4):613-627

 

AllergoOncology: Danger signals in allergology and oncology: A European Academy of Allergy and Clinical Immunology (EAACI) Position Paper.

Bergmann C, Poli A, Agache I, Bianchini R, Bax HJ, Castells M, Crescioli S, Dombrowicz D, Ferastraoaru D, Fiebiger E, Gould HJ, Hartmann K, Izquierdo E, Jordakieva G, Josephs DH, Jutel M, Levi-Schaffer F, de Las Vecillas L, Lotze MT, Osborn G, Pascal M, Redegeld F, Rosenstreich D, Roth-Walter F, Schmidt-Weber C, Shamji M, Steveling EH, Turner MC, Untersmayr E, Jensen-Jarolim E, Karagiannis SN 

Allergy, 2022; 77(9):2594-2617

 

Genome-Wide Gene Expression Analysis Reveals Unique Genes Signatures of Epithelial Reorganization in Primary Airway Epithelium Induced by Type-I, -II and -III Interferons.

Erb A, Zissler UM, Oelsner M, Chaker AM, Schmidt-Weber CB, Jakwerth CA 

Biosensors (Basel), 2022; 12(11)

 

TGF-β1 Drives Inflammatory Th Cell But Not Treg Cell Compartment Upon Allergen Exposure.

Musiol S, Alessandrini F, Jakwerth CA, Chaker AM, Schneider E, Guerth F, Schnautz B, Grosch J, Ghiordanescu I, Ullmann JT, Kau J,  Plaschke M, Haak S, Buch T, Schmidt-Weber CB, Zissler UM

Front Immunol, 2022; 12

 

Drivers of the release of the allergens Bet v 1 and Phl p 5 from birch and grass pollen.

Maya-Manzano JM, Oteros J, Rojo J, Traidl-Hoffmann C, Schmidt-Weber C, Buters J 

Environ Res, 2022; 214(Pt 3)

 

Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases.

Bergant V, Yamada S, Grass V, Tsukamoto Y, Lavacca T, Krey K, Mühlhofer MT, Wittmann S, Ensser A, Herrmann A, Vom Hemdt A, Tomita Y, Matsuyama S, Hirokawa T, Huang Y, Piras A, Jakwerth CA, Oelsner M, Thieme S, Graf A, Krebs S, Blum H, Kümmerer BM, Stukalov A, Schmidt-Weber CB, Igarashi M, Gramberg T, Pichlmair A, Kato H

EMBO J, 2022; 41(17)

 

The priming effect of diesel exhaust on native pollen exposure at the air-liquid interface.

Candeias J, Zimmermann EJ, Bisig C, Gawlitta N, Oeder S, Gröger T, Zimmermann R, Schmidt-Weber CB, Buters J

Environ Res, 2022; 211

 

Non-pharmacological interventions for pollen-induced allergic symptoms: Systematic literature review.

Schutzmeier P, Kutzora S, Mittermeier I, Becker J, Bergmann KC, Böse-O'Reilly S, Buters J, Damialis A, Heinrich J, Kabesch M, Mertes H, Nowak D, Korbely C, Walser-Reichenbach S, Weinberger A, Heinze S, Steckling-Muschack N, Herr C 

Pediatr Allergy Immunol, 2022; 33(1)

 

Immunological effects of adjuvanted low-dose allergoid allergen-specific immunotherapy in experimental murine house dust mite allergy.

Heldner A, Alessandrini F, Russkamp D, Heine S, Schnautz B, Chaker A, Mwange J, Carreno Velazquez TL, Heath MD, Skinner MA, Kramer MF, Zissler UM, Schmidt-Weber CB, Blank S

Allergy, 2022; 77(3):907-919

 

IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33.

Schröder A, Lunding LP, Zissler UM, Vock C, Webering S, Ehlers JC, Orinska Z, Chaker A, Schmidt-Weber CB, Lang NJ, Schiller HB, Mall MA, Fehrenbach H, Dinarello CA, Wegmann M 

Allergy, 2022; 77(3):856-869

 

Secretoglobins in the big picture of immunoregulation in airway diseases.

Mootz M, Jakwerth CA, Schmidt-Weber CB, Zissler UM 

Allergy, 2022; 77(3):767-777

 

The European Curriculum for Additional Qualification Allergology A Position Paper by Medical Association of German Allergologists (AeDA), German Society for Allergology and Clinical Immunology (DGAKI) and Society for Pediatric Allergology and Environmental Medicine (GPA) in   cooperation with European Academy for Allergology and Clinical Immunology (EAACI) and Allergology Section of European Union of Medical Specialists (UEMS)

Muelleneisen N, Klimek L, Worm M, Merk H, Rabe U, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Bergmann AKC, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Matricardi P, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Gerstlauer M, Vogelberg C, Van Wijk RG, Eguiluz-Gracia I, Gayraud J, Gutermuth J, Heffler E, Popov TA, Schmid-Grendelmeier P, Tomazic PV, Tsilochristou O, Del Giacco S, Zuberbier T, Jutel M  

Allergo J, 2021; 30(3):44-53

 

Link between high Pollen Counts and COVID-19 Infections Interesting Theses without final Answers

Bergmann KC, Buters J, Klimek L    

Allergo J, 2021; 30(2):66-67

 

A systematic review of threshold values of pollen concentrations for symptoms of allergy

Steckling-Muschack N, Mertes H, Mittermeier I, Schutzmeier P, Becker J, Bergmann KC, Bose-O'Reilly S, Buters J, Damialis A, Heinrich J, Kabesch M, Nowak D, Walser-Reichenbach S, Weinberger A, Zamfir M, Herr C, Kutzora S, Heinze S 

Aerobiologia (Bologna), 2021; 37(3):395-424

 

Threshold values of grass pollen (Poaceae) concentrations and increase in emergency department visits, hospital admissions, drug consumption and allergic symptoms in patients with allergic rhinitis: a systematic review

Becker J, Steckling-Muschack N, Mittermeier I, Bergmann KC, Boese-O'Reilly S, Buters J, Damialis A, Heigl K, Heinrich J, Kabesch M, Mertes H, Nowak D, Schutzmeier P, Walser-Reichenbach S, Weinberger A, Korbely C, Herr C, Heinze S, Kutzora S 

Aerobiologia (Bologna), 2021; 37(4):633-662

 

Let us introduce ourselves: DGAKI Section of Environmental and Occupational Medicine

Buters J, Raulf M 

Allergologie, 2021; 44(8):663-664

 

Automatic pollen monitoring

Buters J, Gonzalez-Alonso M, Klimek L, Simon JC, Treudler R 

Allergologie, 2021; 44(12):932-942

 

Consequences of climate change on airborne pollen in Bavaria, Central Europe

Rojo J, Picornell A, Oteros J, Werchan M, Werchan B, Bergmann KC, Smith M, Weichenmeier I, Schmidt-Weber CB, Buters J 

Reg. Envir. Chang., 2021; 21(1)

 

Standard methods for Apis mellifera venom research

de Graaf DC, Brochetto Braga MRB, Magalhaes de Abreu RMM, Blank S, Bridts CH, De Clerck LS, Devreese B, Ebo DG, Ferris TJ, Hagendorens MM, Justo Jacomini DLJ, Kanchev I, Kokot ZJ, Matysiak J, Mertens C, Sabato V, Van Gasse AL, Van Vaerenbergh M 

J. Apic. Res., 2021; 60(4)

 

COVID-19 pandemic and allergen immunotherapy-an EAACI survey.

Pfaar O, Agache I, Bonini M, Brough HA, Chivato T, Del Giacco SR, Gawlik R, Gelincik A, Hoffmann-Sommergruber K, Jutel M, Klimek L, Knol EF, Lauerma A, Ollert M, O'Mahony L, Mortz CG, Palomares O, Riggioni C, Schwarze J, Skypala I, Torres MJ, Untersmayr E, Walusiak-Skorupa J, Chaker A, Giovannini M, Heffler E, Jensen-Jarolim E, Quecchia C, Sandoval-Ruballos M, Sahiner U, Tomić Spirić V, Alvaro-Lozano M 

Allergy, 2021; 76(11):3504-3516

 

Severe allergic Reactions after COVID-19 Vaccination with the Pfizer / BioNTech Vaccine in the UK and USA Statement from the German allergological Societies AeDA (Association of German Allergologists), DGAKI (German Society for Allergology and Clinical Immunology) and GPA   (Society for Pediatric Allergology and Environmental Medicine).

Klimek L, Novak N, Hamelmann E, Werfel T, Wagenmann M, Taube C, Bauer A, Merk H, Rabe U, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Mulleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Jakob T, Ankermann T, Schmidt SM, Gerstlauer M, Vogelberg C, Zuberbier T, Hartmann K, Worm M

Allergo J, 2021; 30(2):24-29

 

Positionspapier: Hinweise zur Patienteninformation und -aufklärung vor Anwendung von Biologika bei chronischer Rhinosinusitis mit Nasenpolypen (CRSwNP) – Teil 2: Omalizumab – Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA) und der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC).

Foerster-Ruhrmann U, Beule AG, Becker S, Chaker AM, Huppertz T, Hagemann J, Hoffmann TK, Dazert S, Deitmer T, Wrede H, Schlenter W, Welkoborsky HJ, Wollenberg B, Olze H, Rudack C, Sperl A, Casper I, Dietz A, Wagenmann M, Zuberbier T, Bergmann KC, Bedbrook A, Bousquet J, Bachert C, Bergmann C, Klimek L 

Laryngorhinootologie, 2021; 100(11):864-872

 

Positionspapier: Empfehlungen zur Anwendung von Omalizumab bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem – Empfehlungen des Ärzteverbandes Deutscher Allergologen (AeDA) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC).

Klimek L, Foerster-Ruhrmann U, Beule AG, Chaker AM, Hagemann J, Huppertz T, Hoffmann TK, Dazert S, Deitmer T, Olze H, Strieth S, Wrede H, Schlenter W, Welkoborsky HJ, Wollenberg B, Becker S, Rudack C, Wagenmann M, Bergmann C, Bachert C 

Laryngorhinootologie, 2021; 100(12):952-963

 

Management of patients with seasonal allergic rhinitis: Diagnostic consideration of sensitization to non-frequent pollen allergens.

Höflich C, Balakirski G, Hajdu Z, Baron JM, Fietkau K, Merk HF, Strassen U, Bier H, Dott W, Mücke HG, Straff W, Wurpts G, Yazdi AS, Chaker A, Röseler STM

Clin Transl Allergy, 2021; 11(8)

 

COVID-19-Impfungen: Replizierend oder Nichtreplizierend?

Klimek L, Chaker AM, Cuevas M, Becker S    

Laryngorhinootologie, 2021; 100(8):603-607

 

Allergische Reaktionen auf COVID-19-Impfungen – Was HNO-Ärzte wissen sollten – Teil 1: Allgemeine Aspekte von Allergien auf Impfstoffe, immunologische Grundlagen von Allergien auf Impfstoffe, Immunmechanismen von allergischen und pseudoallergischen Reaktionen, Teil 2: Charakteristiken der mRNA-Impfstoffe BNT162b2 und mRNA-1273 zur Prophylaxe von COVID-19 und assoziierte Immunphänomene, Teil 3: Praktische Aspekte der Prophylaxe, Diagnostik und Therapie von Allergien auf COVID-19-Impfstoffe.

Klimek L, Chaker AM, Cuevas M 

Laryngorhinootologie, 2021; 100(3):168-173

 

Allergic Reactions to COVID-19-Vaccinations - What ENT-Doctors should   know Part 1: General Aspects of Allergies to Vaccines, immunological   Basis of Allergies to Vaccines, Immune Mechanisms of allergic and   pseudo-allergic Reactions Part 2: Characteristics of the mRNA-Vaccines   BNT162b2 and mRNA-1273 for the Prophylaxis of COVID-19, other   Vaccine-Candidates and associated Immune Phenomena Part 3: Practical   aspects of the Prophylaxis, Diagnosis and Treatment of Allergies due to   COVID-19-Vaccines.

Klimek L, Chaker AM, Cuevas M 

Laryngorhinootologie, 2021; 100(4):252-258

 

Allergische Reaktionen auf COVID-19-Impfungen – Was HNO-Ärzte wissen sollten – Teil 1: Immunologische Grundlagen von Allergien auf Impfstoffe, Immunmechanismen von allergischen und pseudoallergischen Reaktionen; Teil 2: Charakteristika der mRNA-Impfstoffe BNT162b2- und mRNA-1273 zur Prophylaxe von COVID-19 und assoziierte Immunphänomene; Teil 3: Praktische Aspekte der Prophylaxe, Diagnostik und Therapie von Allergien auf COVID-19-Impfstoffe.

Klimek L, Chaker AM, Cuevas M 

Laryngorhinootologie, 2021; 100(5):344-354

 

MEK1/2 regulates APOBEC3B and polymerase iota-induced mutagenesis in head and neck cancer cells.

Schulz D, Piontek G, Zissler UM, Multhoff G, Wirth M, Pickhard A  

Am J Cancer Res, 2021; 11(11):5581-5590

 

COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy.

Weckmann M, Bahmer T, Sand JM, Rank Rønnow S, Pech M, Vermeulen C, Faiz A, Leeming DJ, Karsdal MA, Lunding L, Oliver BGG, Wegmann M, Ulrich-Merzenich G, Juergens UR, Duhn J, Laumonnier Y, Danov O, Sewald K, Zissler U, Jonker M, König I, Hansen G, von Mutius E, Fuchs O, Dittrich AM, Schaub B, Happle C, Rabe KF, van de Berge M, Burgess JK, Kopp MV, ALLIANCE Study Group as part of the German Centre for Lung Research (DZL)  

Eur Respir J, 2021; 58(6)

 

Fibroblast growth factor induced Ucp1 expression in preadipocytes requires PGE2 biosynthesis and glycolytic flux.

Gantert T, Henkel F, Wurmser C, Oeckl J, Fischer L, Haid M, Adamski J, Esser-von Bieren J, Klingenspor M, Fromme T 

FASEB J, 2021; 35(5)

 

Macrophage regulation & function in helminth infection.

Lechner A, Bohnacker S, Esser-von Bieren J 

Semin Immunol, 2021; 53

 

Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice.

Papaioannou NE, Salei N, Rambichler S, Ravi K, Popovic J, Küntzel V, Lehmann CHK, Fiancette R, Salvermoser J, Gajdasik DW, Mettler R, Messerer D, Carrelha J, Ohnmacht C, Haller D, Stumm R, Straub T, Jacobsen SEW, Schulz C, Withers DR, Schotta G, Dudziak D, Schraml BU 

Nat Commun, 2021; 12(1)

 

Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism.

Zeitler L, Fiore A, Meyer C, Russier M, Zanella G, Suppmann S, Gargaro M, Sidhu SS, Seshagiri S, Ohnmacht C, Köcher T, Fallarino F, Linkermann A, Murray PJ 

Elife, 2021; 10

 

Keratinocytes Regulate the Threshold of Inflammation by Inhibiting T Cell Effector Functions.

Seiringer P, Eyerich S, Eyerich K, Dittlein D, Pilz AC, Scala E, Ring J, Behrendt H, Cavani A, Traidl-Hoffmann C 

Cells, 2021; 10(7)

 

Comprehensive mapping of immune tolerance yields a regulatory TNF receptor 2 signature in a murine model of successful Fel d 1-specific immunotherapy using high-dose CpG adjuvant.

Leonard C, Montamat G, Davril C, Domingues O, Hunewald O, Revets D, Guerin C, Blank S, Heckendorn J, Jardon G, Hentges F, Ollert M 

Allergy, 2021; 76(7):2153-2165

 

Venom Immunotherapy: From Proteins to Product to Patient Protection.

Feindor M, Heath MD, Hewings SJ, Carreno Velazquez TL, Blank S, Grosch J, Jakob T, Schmid-Grendelmeier P, Klimek L, Golden DBK, Skinner MA, Kramer MF 

Toxins (Basel), 2021; 13(9)

 

Editorial: Novel Advances in Allergy Diagnosis and Treatment.

Blank S, Hilger C 

Front Immunol, 2021; 12

 

CD23 Levels on B Cells Determine Long-Term Therapeutic Response in Patients with Atopic Eczema Treated with Selective IgE Immune Apheresis.

Thomas J, Wang R, Batra R, Böhner A, Garzorz-Stark N, Eberlein B, Theis F, Biedermann T, Schmidt-Weber C, Zink A, Eyerich K, Eyerich S 

J Invest Dermatol, 2021; 141(3):681-685.e6

 

Allergen-specific immunotherapy induces the suppressive secretoglobin 1A1 in cells of the lower airways.

Zissler UM, Jakwerth CA, Guerth F, Lewitan L, Rothkirch S, Davidovic M, Ulrich M, Oelsner M, Garn H, Schmidt-Weber CB, Chaker AM 

Allergy, 2021; 76(8):2461-2474

 

Sputum microRNA-screening reveals Prostaglandin EP3 receptor as selective target in allergen-specific immunotherapy.

Jakwerth CA, Chaker AM, Guerth F, Oelsner M, Pechtold L, Zur Bonsen LS, Ullmann JT, Krauss-Etschmann S, Erb A, Kau J, Plaschke M, Winkler M, Kurz A, Kloss A, Esser-von Bieren J, Schmidt-Weber CB, Zissler UM 

Clin Exp Allergy, 2021; 51(12):1577-1591

 

Inflammatory macrophage memory in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease.

Haimerl P, Bernhardt U, Schindela S, Henkel FDR, Lechner A, Zissler UM, Pastor X, Thomas D, Cecil A, Ge Y, Haid M, Prehn C, Tokarz J, Heinig M, Adamski J, Schmidt-Weber CB, Chaker AM, Esser-von Bieren J 

J Allergy Clin Immunol, 2021; 147(2):587-599

 

Characterization of New Allergens from the Venom of the European Paper Wasp Polistes dominula.

Grosch J, Eberlein B, Waldherr S, Pascal M, San Bartolomé C, De La Roca Pinzón F, Dittmar M, Hilger C, Ollert M, Biedermann T, Darsow U, Bilò MB, Schmidt-Weber CB, Blank S 

Toxins (Basel), 2021; 13(8)

 

The component-based basophil activation test as a decisive in vitro test to detect sensitization in cases of insect venom allergy

Bernadette Eberlein, Paul Schmidle, Simon Blank, Felix King, Tilo Biedermann, Ulf Darsow, Knut Brockow

Allergologie, 2021; 44(8):615-618

 

Constitutive immune activity promotes JNK- and FoxO-dependent remodeling of Drosophila airways.

Wagner C, Uliczka K, Bossen J, Niu X, Fink C, Thiedmann M, Knop M, Vock C, Abdelsadik A, Zissler UM, Isermann K, Garn H, Pieper M, Wegmann M, Koczulla AR, Vogelmeier CF, Schmidt-Weber CB,  Fehrenbach H, König P, Silverman N, Renz H, Pfefferle P, Heine H, Roeder T 

Cell Rep, 2021; 35(1)

 

Marker allergens in Hymenoptera venom allergy - Characteristics and potential use in precision medicine

Simon Blank, Maria Beatrice Bilò, Johannes Grosch, Carsten B. Schmidt-Weber, Markus Ollert, Thilo Jakob

Allergo J Int, 2021; 30:26-38

 

Effects of future climate change on birch abundance and their pollen load.

Rojo J, Oteros J, Picornell A, Maya-Manzano JM, Damialis A, Zink K, Werchan M, Werchan B, Smith M, Menzel A, Timpf S, Traidl-Hoffmann C, Bergmann KC, Schmidt-Weber CB, Buters J  

Glob Chang Biol, 2021; 27(22):5934-5949

 

An exhausted phenotype of TH 2 cells is primed by allergen exposure, but not reinforced by allergen-specific immunotherapy.

Wang SH, Zissler UM, Buettner M, Heine S, Heldner A, Kotz S, Pechtold L, Kau J, Plaschke M, Ullmann JT, Guerth F, Oelsner M, Alessandrini F, Blank S, Chaker AM, Schmidt-Weber CB, Jakwerth CA  

Allergy, 2021; 76(9):2827-2839

 

Dosing intact birch pollen grains at the air-liquid interface (ALI) to the immortalized human bronchial epithelial cell line BEAS-2B.

Candeias J, Schmidt-Weber CB, Buters J 

PLoS ONE, 2021; 16(11)

 

Noninvasive and minimally invasive techniques for the diagnosis and management of allergic diseases.

Baumann R, Untersmayr E, Zissler UM, Eyerich S, Adcock IM, Brockow K, Biedermann T, Ollert M, Chaker AM, Pfaar O, Garn H, Thwaites RS, Togias A, Kowalski ML, Hansel T, Jakwerth C, Schmidt-Weber CB 

Allergy, 2021; 76(4):1010-1023

 

Asymmetric Overgrowth and a Facial Port Wine Stain.

Seiringer P, Biedermann T, Schnopp C 

J Pediatr, 2021; 229:300-301

 

Ragweed plants grown under elevated CO2 levels produce pollen which elicit stronger allergic lung inflammation.

Rauer D, Gilles S, Wimmer M, Frank U, Mueller C, Musiol S, Vafadari B, Aglas L, Ferreira F, Schmitt-Kopplin P, Durner J, Winkler JB, Ernst D, Behrendt H, Schmidt-Weber CB, Traidl-Hoffmann C, Alessandrini F 

Allergy, 2021; 76(6):1718-1730

 

Spotlight on microRNAs in allergy and asthma.

Weidner J, Bartel S, Kılıç A, Zissler UM, Renz H, Schwarze J, Schmidt-Weber CB, Maes T, Rebane A, Krauss-Etschmann S, Rådinger M 

Allergy, 2021; 76(6):1661-1678

 

Predicting persistence of atopic dermatitis in children using clinical attributes and serum proteins.

Lauffer F, Baghin V, Standl M, Stark SP, Jargosch M, Wehrle J, Thomas J, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K, Garzorz-Stark N 

Allergy, 2021; 76(4):1158-1172

 

Pollen calendars and regional gradients as information tools in the  Extremadura pollen monitoring network (SW Spain)

Pecero-Casimiro R, Maya-Manzano JM, Fernandez-Rodriguez S, Tormo-Molina R, Silva-Palacios I, Monroy-Colin A, Gonzalo-Garijo A 

Aerobiologia (Bologna), 2020; 36(4):731-748

 

Phenology of Cupressaceae urban infrastructure related to its pollen content and meteorological variables

Monroy-Colin A, Maya-Manzano JM, Silva-Palacios I, Tormo-Molina R, Pecero-Casimiro R, Gonzalo-Garijo A, Fernandez-Rodriguez S 

Aerobiologia (Bologna), 2020; 36(3):459-479

 

Producing Urban Aerobiological Risk Map for Cupressaceae Family in the SW Iberian Peninsula from LiDAR Technology

Pecero-Casimiro R, Fernandez-Rodriguez S, Tormo-Molina R, Silva-Palacios I, Gonzalo-Garijo A, Monroy-Colin A, Francisco Coloma JF, Maya-Manzano JM 

Remote Sens., 2020; 12(10)

 

HYSPLIT as an environmental impact assessment tool to study the data discrepancies between Olea europaea airborne pollen records and its   phenology in SW Spain

Monroy-Colin A, Maria Maya-Manzano JM, Tormo-Molina R, Pecero-Casimiro R, Angeles Gonzalo-Garijo MA, Fernandez-Rodriguez S 

URBAN FORESTRY & URBAN GREENING, 2020; 53

 

Occupational rhinitis

Kotz S, Pechtold L, Joerres RA, Nowak D, Chaker AM 

Allergologie, 2020; 43(6):239-246

 

The therapy of allergic rhinitis in routine care: evidence-based benefit assessment of the combined use of several active ingredients

Klimek L, Casper I, Bergmann KC, Biedermann T, Bousquet J, Hellings P, Jung K, Merk H, Olze H, Moesges R, Schlenter W, Groeger M, Ring J, Chaker A, Pfaar O, Wehrmann W, Zuberbier T, Becker S 

Allergologie, 2020; 43(11):476-488

 

Allergen immuntherapy in the current COVID-19 pandemic - A position paper of ARIA, EAACI, AeDA, DGAKI, and GPA

Klimek L, Pfaar O, Worm M, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Mosges R, Saloga J, Staubach P, Stute P, Rabe K, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Mulleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink-Wagner A, Horak F, Wohrl S, Niederberger-Leppin V, Pali-Scholl I, Pohl W, Roller-Wirnsberger R, Spranger O, Valenta R, Akdis M, Akdis C, Hoffmann-Sommergruber K, Jutel M, Matricardi P, Spertini F, Khaltaev N, Michel JP, Nicod L, Schmid-Grendelmeier P, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Bousquet J, Zuberbier T, Vogelberg C, Gerstlauer M, Deutsch ARIA-Grp, Osterreichischen ARIA-Grp, Schweizerischen ARIA-Grp, Arzteverband Deutsch Allergologen, Deutsch Gesell Allergologie Klin, Gesell Padiatrische Allergologie G, Kooperation Mit AG Klinische Immun, Europaischen Akad Allergologie K  

Allergologie, 2020; 43(5):165-175

 

Intentional introduction pathways of alien birds and mammals in Latin America

Carpio AJ, Alvarez Y, Oteros J, Leon F, Tortosa FS 

Glob. Ecol. Conserv., 2020; 22

 

High post-season Alnus pollen loads successfully identified as long-range transport of an alpine species

Ghasemifard H, Ghada W, Estrella N, Luepke M, Oteros J, Traidl-Hoffmann C, Damialis A, Buters J, Menzel A 

Atmos. Environ., 2020; 231

 

Use of biologicals in allergic and type 2 inflammatory diseases in the current COVID 19 pandemic

Klimek L, Pfaar O, Worm M, Eiwegger T, Hagemann J, Ollert M, Untersmayr E, Hoffmann-Sommergruber K, Vultaggio A, Agache I, Bavbek S, Bossios A, Casper I, Chan S, Chatzipetrou A, Vogelberg C, Firinu D, Kauppi P, Kolios A, Kothari A, Matucci A, Palomares O, Szepfalusi Z, Pohl W, Hoetzenecker W, Rosenkranz A, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Moesges R, Saloga J, Staubach P, Jappe U, Rabe C, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Freudelsperger L, Muelleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink-Wagner A, Horak F, Woehrl S, Niederberger-Leppin V, Pali-Schoell I, Roller-Wirnsberger R, Spranger O, Valenta R, Akdis M, Matricardi PM, Spertini F, Khaltaev N, Michel JP, Nicod L, Schmid-Grendelmeier P, Idzko M, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Jensen-Jarolim E, Korn S, Hentges F, Schwarze J, OMahony L, Knol E, del Giacco S, Chivato Perez TC, Bousquet J, Zuberbier T, Akdis C, Jutel M 

Allergologie, 2020; 43(7):255-271

 

Perspectives for a nationwide Pollen Monitoring in Germany Interdisciplinary Working Group for "Nationwide Pollen Monitoring"

Baeker R, Bergmann KC, Buters J, Durnmel T, Endler C, Fuchs T, Gilge S, Gloyna K, Heesen R, Herr C, Hicke M, Hoflich C, Klimek L, Kutzora S, Langner M, Mucke HG, Petzold G, Pleschka S, Roseler S, Schwalfenberg A, Simon S, Straff W, Weber A, Werchan B, Werchan M 

Allergologie, 2020; 43(3):111-124

 

Land-Use and Height of Pollen Sampling Affect Pollen Exposure in Munich, Germany

Rojo J, Oteros J, Picornell A, Rueff F, Werchan B, Werchan M, Bergmann KC, Schmidt-Weber CB, Buters J 

Atmosphere, 2020; 11(2)

 

ARIA Guideline 2019: Treatment of allergic Rhinitis in the German Healthcare System

Klimek L, Bachert C, Pfaar O, Becker S, Bieber T, Brehler R, Buhl R, Casper I, Chaker A, Czech W, Fischer J, Fuchs T, Gerstlauer M, Hoermann K, Jakob T, Jung K, Kopp MV, Mahler V, Merk H, Mulleneisen N, Nemat K, Rabe U, Ring J, Saloga J, Schlenter W, Schmidt-Weber C, Seyfarth H, Sperl A, Spindler T, Staubach P, Strieth S, Treudler R, Vogelberg C, Wallrafen A, Wehrmann W, Wrede H, Zuberbier T, Bedbrook A, Canonica GW, Cardona V, Casale TB, Czariewski W, Fokkens WJ, Hamelmann E, Hellings PW, Jute M, Larenas-Linnemann D, Mullol J, Papadopoulos NG, Toppila-Salmi S, Werfel T, Bousquet J 

Allergologie, 2020; 43(2):43-72

 

Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae.

Coakley G, Volpe B, Bouchery T, Shah K, Butler A, Geldhof P, Hatherill M, Horsnell WGC, Esser-von Bieren J, Harris NL   

Parasite Immunol, 2020; 42(7)

 

Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice.

Aguilar-Pimentel JA, Cho YL, Gerlini R, Calzada-Wack J, Wimmer M, Mayer-Kuckuk P, Adler T, Schmidt-Weber CB, Busch DH, Fuchs H, Gailus-Durner V, Ollert M, Hrabě de Angelis M, Ohlsson C, Poutanen M, Teperino R, Strauss L  

Sci Rep, 2020; 10(1)

 

Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and Aging.

Timofeev O, Koch L, Niederau C, Tscherne A, Schneikert J, Klimovich M, Elmshäuser S, Zeitlinger M, Mernberger M, Nist A, Osterburg C, Dötsch V, Hrabé de Angelis M, Stiewe T, German Mouse Clinic Consortium   

Cancer Res, 2020; 80(23):5231-5244

 

Precision Medicine in Hymenoptera Venom Allergy: Diagnostics, Biomarkers, and Therapy of Different Endotypes and Phenotypes.

Blank S, Grosch J, Ollert M, Bilò MB 

Front Immunol, 2020; 11

 

Mimicking Antigen-Driven Asthma in Rodent Models-How Close Can We Get?

Alessandrini F, Musiol S, Schneider E, Blanco-Pérez F, Albrecht M 

Front Immunol, 2020; 11

 

Mixture Analyses of Air-sampled Pollen Extracts Can Accurately Differentiate Pollen Taxa.

Klimczak LJ, von Eschenbach CE, Thompson PM, Buters JTM, Mueller GA

Atmos. Environ., 2020; 243:117746

 

[Therapy of Allergies and Allergy Immunotherapy in Children].

Klimek L, Chaker AM, Casper I, Sperl A, Strieth S, Mösges R    

Laryngorhinootologie, 2020; 99(1):56-66

 

Allergen immunotherapy in the current COVID-19 pandemic: A position paper of AeDA, ARIA, EAACI, DGAKI and GPA: Position paper of the German ARIA GroupA in cooperation with the Austrian ARIA GroupB, the Swiss ARIA GroupC, German Society for Applied Allergology (AEDA)D, German Society for Allergology and Clinical Immunology (DGAKI)E, Society for Pediatric Allergology (GPA)F in cooperation with AG Clinical Immunology, Allergology and Environmental Medicine of the DGHNO-KHCG and the European Academy of Allergy and Clinical Immunology (EAACI)H.

Klimek L, Pfaar O, Worm M, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Mösges R, Saloga J, Staubach P, Stute P, Rabe K, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Mülleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink-Wagner A, Horak F, Wöhrl S, Niederberger-Leppin V, Pali-Schöll I, Pohl W, Roller-Wirnsberger R, Spranger O, Valenta R, Akdis M, Akdis C, Hoffmann-Sommergruber K, Jutel M, Matricardi P, Spertin F, Khaltaev N, Michel JP, Nicod L, Schmid-Grendelmeier P, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Gerstlauer M, Vogelberg C, Bousquet J, Zuberbier T    

Allergol Select , 2020; 4:44-52

 

Allergen-Immuntherapie in der aktuellen Covid-19-Pandemiea, b, c.

Klimek L, Pfaar O, Worm M, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Mösges R, Saloga J, Staubach P, Poethig D, Rabe K, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Mülleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink-Wagner A, Horak F, Wöhrl S, Niederberger-Leppin V, Pali-Schöll I, Pohl W, Roller-Wirnsberger R, Spranger O, Valenta R, Akdis M, Akdis C, Hoffmann-Sommergruber K, Jutel M, Matricardi P, Spertini F, Khaltaev N, Michel JP, Nicod L, Schmid-Grendelmeier P, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Bousquet J, Zuberbier T, Vogelberg C, Gerstlauer M    

Allergo J, 2020; 29(3):17-25

 

Immunology of COVID-19: Mechanisms, clinical outcome, diagnostics, and perspectives-A report of the European Academy of Allergy and Clinical Immunology (EAACI).

Sokolowska M, Lukasik ZM, Agache I, Akdis CA, Akdis D, Akdis M, Barcik W, Brough HA, Eiwegger T, Eljaszewicz A, Eyerich S, Feleszko W, Gomez-Casado C, Hoffmann-Sommergruber K, Janda J, Jiménez-Saiz R, Jutel M, Knol EF, Kortekaas Krohn I, Kothari A, Makowska J, Moniuszko M, Morita H, O'Mahony L, Nadeau K, Ozdemir C, Pali-Schöll I, Palomares O, Papaleo F, Prunicki M, Schmidt-Weber CB, Sediva A, Schwarze J, Shamji MH, Tramper-Stranders GA, van de Veen W, Untersmayr E   

Allergy, 2020; 75(10):2445-2476

 

An operational robotic pollen monitoring network based on automatic image recognition.

Oteros J, Weber A, Kutzora S, Rojo J, Heinze S, Herr C, Gebauer R, Schmidt-Weber CB, Buters JTM  

Environ Res, 2020; 191:110031

 

Atmospheric pollutants and their association with olive and grass aeroallergen concentrations in Córdoba (Spain).

Plaza MP, Alcázar P, Oteros J, Galán C 

Environ Sci Pollut Res Int, 2020; 27(36):45447-45459

 

Influence of glycosylation on IL-12 family cytokine biogenesis and function.

Bohnacker S, Hildenbrand K, Aschenbrenner I, Müller SI, Bieren JE, Feige MJ  

Mol Immunol, 2020; 126:120-128

 

More Than Just a Barrier: The Immune Functions of the Airway Epithelium in Asthma Pathogenesis.

Frey A, Lunding LP, Ehlers JC, Weckmann M, Zissler UM, Wegmann M 

Front Immunol, 2020; 11:761

 

Clinical relevance of Aspergillus fumigatus sensitization in cystic fibrosis.

Eickmeier O, Zissler UM, Wittschorek J, Unger F, Schmitt-Grohé S, Schubert R, Herrmann E, Zielen S 

Clin Exp Allergy, 2020; 50(3):325-333

 

COVID-19 and immunological regulations - from basic and translational aspects to clinical implications.

Schön MP, Berking C, Biedermann T, Buhl T, Erpenbeck L, Eyerich K, Eyerich S, Ghoreschi K, Goebeler M, Ludwig RJ, Schäkel K, Schilling B, Schlapbach C, Stary G, von Stebut E, Steinbrink K 

J Dtsch Dermatol Ges, 2020; 18(8):795-807

 

A compendium answering 150 questions on COVID-19 and SARS-CoV-2.

Riggioni C, Comberiati P  Giovannini M  Agache I, Akdis M, Alves-Correia M  Antó JM, Arcolaci A  Azkur AK, Azkur D, Beken B, Boccabella C, Bousquet J, Breiteneder H, Carvalho D, De Las Vecillas L, Diamant Z, Eguiluz-Gracia I, Eiwegger T, Eyerich S, Fokkens W, Gao YD, Hannachi F, Johnston SL, Jutel M, Karavelia A, Klimek L, Moya B, Nadeau KC, O'Hehir R, O'Mahony L, Pfaar O, Sanak M, Schwarze J, Sokolowska M, Torres MJ, van de Veen W, van Zelm MC, Wang Y, Zhang L, Jiménez-Saiz R, Akdis CA

Allergy, 2020; 75(10):2503-2541

 

Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal.

Baumann T, Dunkel A, Schmid C, Schmitt S, Hiltensperger M, Lohr K, Laketa V, Donakonda S, Ahting U, Lorenz-Depiereux B, Heil JE, Schredelseker J, Simeoni L, Fecher C, Körber N, Bauer T, Hüser N, Hartmann D, Laschinger M, Eyerich K, Eyerich S, Anton M, Streeter M, Wang T, Schraven B, Spiegel D, Assaad F, Misgeld T, Zischka H, Murray PJ, Heine A, Heikenwälder M, Korn T, Dawid C, Hofmann T, Knolle PA, Höchst B 

Nat Immunol, 2020; 21(5):555-566

 

Nutrition and the Immune System: A Complicated Tango.

Venter C, Eyerich S, Sarin T, Klatt KC 

Nutrients, 2020; 12(3):818

 

New biological treatments for asthma and skin allergies.

Eyerich S, Metz M, Bossios A, Eyerich K 

Allergy, 2020; 75(3):546-560

 

Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020.

Maurer M, Eyerich K, Eyerich S, Ferrer M, Gutermuth J, Hartmann K, Jakob T, Kapp A, Kolkhir P, Larenas-Linnemann D, Park HS, Pejler G, Sánchez-Borges M, Schäkel K, Simon D, Simon HU, Weller K, Zuberbier T, Metz M 

Int Arch Allergy Immunol, 2020; 181(5):321-333

 

The Honeybee Venom Major Allergen Api m 10 (Icarapin) and Its Role in Diagnostics and Treatment of Hymenoptera Venom Allergy.

Jakob T, Rauber MM, Perez-Riverol A, Spillner E, Blank S 

Curr Allergy Asthma Rep, 2020; 20(9):48

 

Therapeutic Potential of the Intestinal Microbiota for Immunomodulation of Food Allergies.

Kreft L, Hoffmann C, Ohnmacht C 

Front Immunol, 2020; 11:1853

 

The development of birch pollen seasons over 30 years in Munich, Germany-An EAACI Task Force report.

Bergmann KC, Buters J, Karatzas K, Tasioulis T, Werchan B, Werchan M, Pfaar O 

Allergy, 2020; 75(12):3024-3026

 

Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.

Ihantola T, Di Bucchianico S, Happo M, Ihalainen M, Uski O, Bauer S, Kuuspalo K, Sippula O, Tissari J, Oeder S, Hartikainen A, Rönkkö TJ, Martikainen MV, Huttunen K, Vartiainen P, Suhonen H, Kortelainen M, Lamberg H, Leskinen A, Sklorz M, Michalke B, Dilger M, Weiss C, Dittmar G, Beckers J, Irmler M, Buters J, Candeias J, Czech H, Yli-Pirilä P, Abbaszade G, Jakobi G, Orasche J, Schnelle-Kreis J, Kanashova T, Karg E, Streibel T, Passig J, Hakkarainen H, Jokiniemi J, Zimmermann R, Hirvonen MR, Jalava PI 

Part Fibre Toxicol, 2020; 17(1):27

 

Pollen season is reflected on symptom load for grass and birch pollen-induced allergic rhinitis in different geographic areas-An EAACI Task Force Report.

Pfaar O, Karatzas K, Bastl K, Berger U, Buters J, Darsow U, Demoly P, Durham SR, Galán C, Gehrig R, Gerth van Wijk R, Jacobsen L, Katsifarakis N, Klimek L, Saarto A, Sofiev M, Thibaudon M, Werchan B, Bergmann KC 

Allergy, 2020; 75(5):1099-1106

 

[Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI-AeDA-GPA-DGAKI Position Paper (Pocket-Guide)].

Pfaar O, Klimek L, Worm M, Bergmann KC, Bieber T, Buhl R, Buters J, Darsow U, Keil T, Kleine-Tebbe J, Lau S, Maurer M, Merk H, Mösges R, Saloga J, Staubach P, Stute P, Rabe K, Rabe U, Vogelmeier C, Biedermann T, Jung K, Schlenter W, Ring J, Chaker A, Wehrmann W, Becker S, Mülleneisen N, Nemat K, Czech W, Wrede H, Brehler R, Fuchs T, Tomazic PV, Aberer W, Fink-Wagner A, Horak F, Wöhrl S, Niederberger-Leppin V, Pali-Schöll I, Pohl W, Roller-Wirnsberger R, Spranger O, Valenta R, Akdis M, Akdis C,  Hoffmann-Sommergruber K, Jutel M, Matricardi P, Spertini F, Khaltaev N, Michel JP, Nicod L, Schmid-Grendelmeier P, Hamelmann E, Jakob T, Werfel T, Wagenmann M, Taube C, Gerstlauer M, Vogelberg C, Bousquet J, Zuberbier T

Laryngorhinootologie, 2020;  99(10): 676-679

 

Understanding hourly patterns of Olea pollen concentrations as tool for the environmental impact assessment.

Fernández-Rodríguez S, Maya-Manzano JM, Colín AM, Pecero-Casimiro R, Buters J, Oteros J 

Sci Total Environ, 2020; 736:139363

 

Shedding Light on the Venom Proteomes of the Allergy-Relevant Hymenoptera Polistes dominula (European Paper Wasp) and Vespula spp. (Yellow Jacket).

Grosch J, Hilger C, Bilò MB, Kler S, Schiener M, Dittmar G, Bernardin F, Lesur A, Ollert M, Schmidt-Weber CB, Blank S 

Toxins (Basel), 2020; 12(5):323

 

An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products.

de Los Reyes Jiménez M, Lechner A, Alessandrini F, Bohnacker S, Schindela S, Trompette A, Haimerl P, Thomas D, Henkel F, Mourão A, Geerlof A, da Costa CP, Chaker AM, Brüne B, Nüsing R, Jakobsson PJ, Nockher WA, Feige MJ, Haslbeck M, Ohnmacht C, Marsland BJ, Voehringer D, Harris NL, Schmidt-Weber CB, Esser-von Bieren J 

Sci Transl Med, 2020; 12(540)

 

State-of-the-art in marketed adjuvants and formulations in Allergen Immunotherapy: A position paper of the European Academy of Allergy and Clinical Immunology (EAACI).

Jensen-Jarolim E, Bachmann MF, Bonini S, Jacobsen L, Jutel M, Klimek L, Mahler V, Mösges R, Moingeon P, O Hehir RE, Palomares O, Pfaar O, Renz H, Rhyner C, Roth-Walter F, Rudenko M, Savolainen J, Schmidt-Weber CB, Traidl-Hoffmann C, Kündig T 

Allergy, 2020; 75(4):746-760

 

In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.

Lucienne M, Aguilar-Pimentel JA, Amarie OV, Becker L, Calzada-Wack J, da Silva-Buttkus P, Garrett L, Hölter SM, Mayer-Kuckuk P, Rathkolb B, Rozman J, Spielmann N, Treise I, Busch DH, Klopstock T, Schmidt-Weber C, Wolf E, Wurst W, Forny M, Mathis D, Fingerhut R, Froese DS, Gailus-Durner V, Fuchs H, de Angelis MH, Baumgartner MR 

Biochim Biophys Acta Mol Basis Dis, 2020; 1866(3):165622

 

Biologicals in allergic diseases and asthma: Toward personalized medicine and precision health: Highlights of the 3rd EAACI Master Class on Biologicals, San Lorenzo de El Escorial, Madrid, 2019.

Palomares O, Untersmayr E, Gutermuth J, Agache I, Ajeganova S, Bavbek S, Chan S, Jutel M, Quirce S, Schmid-Grendelmeier P, Schmidt-Weber C, Torres MJ, Eiwegger T 

Allergy, 2020; 75(4):936-940

 

IgE autoantibodies and autoreactive T cells and their role in children and adults with atopic dermatitis.

Badloe FMS, De Vriese S, Coolens K, Schmidt-Weber CB, Ring J, Gutermuth J, Kortekaas Krohn I 

Clin Transl Allergy, 2020; 10(1):34

 

In-vivo diagnostic test allergens in Europe: A call to action and proposal for recovery plan-An EAACI position paper.

Klimek L, Hoffmann HJ, Kalpaklioglu AF, Demoly P, Agache I, Popov TA, Muraro A, Schmid-Grendelmeier P, Bonini S, Bonertz A, Mahler V, Vieths S, Pfaar O, Zuberbier T, Jutel M, Schmidt-Weber C, Hellings PW, Dreborg S, Bonini M, Brough HA, Bousquet J, Hoffmann-Sommergruber K, Palomares O, Ollert M, Shamji MH, Cardona V 

Allergy, 2020; 75(9):2161-2169

 

Predicting Success of Allergen-Specific Immunotherapy.

Zissler UM, Schmidt-Weber CB 

Front Immunol, 2020; 11:1826

 

Antigen 5 Allergens of Hymenoptera Venoms and Their Role in Diagnosis and Therapy of Venom Allergy.

Blank S, Bazon ML, Grosch J, Schmidt-Weber CB, Brochetto-Braga MR, Bilò MB, Jakob T

Curr Allergy Asthma Rep., 2020; 20(10):58

 

IL-17C amplifies epithelial inflammation in human psoriasis and atopic eczema.

Lauffer F, Jargosch M, Baghin V, Krause L, Kempf W, Absmaier-Kijak M, Morelli M, Madonna S, Marsais F, Lepescheux L, Albanesi C, Müller NS, Theis FJ, Schmidt-Weber C, Eyerich S, Biedermann T, Vandeghinste N, Steidl S, Eyerich K 

J Eur Acad Dermatol Venereol 2020; 34(4):800-809

 

Fatal anaphylaxis following a hornet sting in a yellow jacket venom-sensitized patient with undetected monoclonal mast cell activation syndrome and without previous history of a systemic sting reaction.

Blank S, Pehlivanli S, Methe H, Schmidt-Weber CB, Biedermann T, Horny HP, Kristensen T, Amar Y, Köberle M, Brockow K, Stömmer PE 

J Allergy Clin Immunol Pract, 2020;  8(1):401-403.e2

 

The role of mobile health technologies in allergy care: An EAACI position paper.

Matricardi PM, Dramburg S, Alvarez-Perea A, Antolín-Amérigo D, Apfelbacher C, Atanaskovic-Markovic M, Berger U, Blaiss MS, Blank S, Boni E, Bonini M, Bousquet J, Brockow K, Buters J, Cardona V, Caubet JC, Cavkaytar Ö, Elliott T, Esteban-Gorgojo I, Fonseca JA, Gardner J, Gevaert P, Ghiordanescu I, Hellings P, Hoffmann-Sommergruber K, Fusun Kalpaklioglu A, Marmouz F, Meijide Calderón Á, Mösges R, Nakonechna A, Ollert M, Oteros J, Pajno G, Panaitescu C, Perez-Formigo D, Pfaar O, Pitsios C, Rudenko M, Ryan D, Sánchez-García S, Shih J, Tripodi S, Van der Poel LA, van Os-Medendorp H, Varricchi G, Wittmann J, Worm M, Agache I 

Allergy, 2020; 75(2):259-272.

 

Thomas J, Küpper M, Batra R, Jargosch M, Atenhan A, Baghin V, Krause L, Lauffer F, Biedermann T, Theis FJ, Eyerich K, Schmidt-Weber CB, Eyerich S, Garzorz-Stark N. Is the humoral immunity dispensable for the pathogenesis of psoriasis? J Eur Acad Dermatol Venereol. 2019;33(1):115-22.10.1111/jdv.15101

Thomas J, Küpper M, Batra R, Jargosch M, Atenhan A, Baghin V, Krause L, Lauffer F, Biedermann T, Theis FJ, Eyerich K, Schmidt-Weber CB, Eyerich S, Garzorz-Stark N. Corrigendum: Is the humoral immunity dispensable for the pathogenesis of psoriasis? J Eur Acad Dermatol Venereol. 2019;33(12):2380.10.1111/jdv.16019

Russkamp D, Aguilar-Pimentel A, Alessandrini F, Gailus-Durner V, Fuchs H, Ohnmacht C, Chaker A, de Angelis MH, Ollert M, Schmidt-Weber CB, Blank S. IL-4 receptor α blockade prevents sensitization and alters acute and long-lasting effects of allergen-specific immunotherapy of murine allergic asthma. Allergy. 2019;74(8):1549-60.10.1111/all.13759

Rojo J, Oteros J, Pérez-Badia R, Cervigón P, Ferencova Z, Gutiérrez-Bustillo AM, Bergmann KC, Oliver G, Thibaudon M, Albertini R, Rodríguez-De la Cruz D, Sánchez-Reyes E, Sánchez-Sánchez J, Pessi AM, Reiniharju J, Saarto A, Calderón MC, Guerrero C, Berra D, Bonini M, Chiodini E, Fernández-González D, García J, Trigo MM, Myszkowska D, Fernández-Rodríguez S, Tormo-Molina R, Damialis A, Kolek F, Traidl-Hoffmann C, Severova E, Caeiro E, Ribeiro H, Magyar D, Makra L, Udvardy O, Alcázar P, Galán C, Borycka K, Kasprzyk I, Newbigin E, Adams-Groom B, Apangu GP, Frisk CA, Skjøth CA, Radišić P, Šikoparija B, Celenk S, Schmidt-Weber CB, Buters J. Near-ground effect of height on pollen exposure. Environ Res. 2019;174:160-9.10.1016/j.envres.2019.04.027

Picornell A, Buters J, Rojo J, Traidl-Hoffmann C, Damialis A, Menzel A, Bergmann KC, Werchan M, Schmidt-Weber C, Oteros J. Predicting the start, peak and end of the Betula pollen season in Bavaria, Germany. Sci Total Environ. 2019;690:1299-309.10.1016/j.scitotenv.2019.06.485

Pfaar O, Agache I, de Blay F, Bonini S, Chaker AM, Durham SR, Gawlik R, Hellings PW, Jutel M, Kleine-Tebbe J, Klimek L, Kopp MV, Nandy A, Rabin RL, van Ree R, Renz H, Roberts G, Salapatek AM, Schmidt-Weber CB, Shamji MH, Sturm GJ, Virchow JC, Wahn U, Willers C, Zieglmayer P, Akdis CA. Perspectives in allergen immunotherapy: 2019 and beyond. Allergy. 2019;74 Suppl 108:3-25.10.1111/all.14077

Oteros J, Sofiev M, Smith M, Clot B, Damialis A, Prank M, Werchan M, Wachter R, Weber A, Kutzora S, Heinze S, Herr CEW, Menzel A, Bergmann KC, Traidl-Hoffmann C, Schmidt-Weber CB, Buters JTM. Building an automatic pollen monitoring network (ePIN): Selection of optimal sites by clustering pollen stations. Sci Total Environ. 2019;688:1263-74.10.1016/j.scitotenv.2019.06.131

Oteros J, Bartusel E, Alessandrini F, Núñez A, Moreno DA, Behrendt H, Schmidt-Weber C, Traidl-Hoffmann C, Buters J. Artemisia pollen is the main vector for airborne endotoxin. J Allergy Clin Immunol. 2019;143(1):369-77.e5.10.1016/j.jaci.2018.05.040

Klimek L, Bachert C, Pfaar O, Becker S, Bieber T, Brehler R, Buhl R, Casper I, Chaker A, Czech W, Fischer J, Fuchs T, Gerstlauer M, Hörmann K, Jakob T, Jung K, Kopp MV, Mahler V, Merk H, Mülleneisen N, Nemat K, Rabe U, Ring J, Saloga J, Schlenter W, Schmidt-Weber C, Seyfarth H, Sperl A, Spindler T, Staubach P, Strieth S, Treudler R, Vogelberg C, Wallrafen A, Wehrmann W, Wrede H, Zuberbier T, Bedbrook A, Canonica GW, Cardona V, Casale TB, Czarlewski W, Fokkens WJ, Hamelmann E, Jutel M, Larenas-Linnemann D, Mullol J, Papadopoulos NG, Toppila-Salmi S, Werfel T, Bousquet J. ARIA guideline 2019: treatment of allergic rhinitis in the German health system. Allergol Select. 2019;3(1):22-50.10.5414/alx02120e

Henkel FDR, Friedl A, Haid M, Thomas D, Bouchery T, Haimerl P, de Los Reyes Jiménez M, Alessandrini F, Schmidt-Weber CB, Harris NL, Adamski J, Esser-von Bieren J. House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions. Allergy. 2019;74(6):1090-101.10.1111/all.13700

Gutermuth J, Schmidt-Weber CB, Blank S. Supporting allergen-specific immunotherapy by inhibition of Janus kinases. Allergy. 2019;74(9):1814-6.10.1111/all.13808

Andreas N, Potthast M, Geiselhöringer AL, Garg G, de Jong R, Riewaldt J, Russkamp D, Riemann M, Girard JP, Blank S, Kretschmer K, Schmidt-Weber C, Korn T, Weih F, Ohnmacht C. RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells. J Immunol. 2019;203(10):2602-13.10.4049/jimmunol.1801530

Agache I, Annesi-Maesano I, Bonertz A, Branca F, Cant A, Fras Z, Ingenrieth F, Namazova-Baranova L, Odemyr M, Spanevello A, Vieths S, Yorgancioglu A, Alvaro-Lozano M, Barber Hernandez D, Chivato T, Del Giacco S, Diamant Z, Eguiluz-Gracia I, van Wijk RG, Gevaert P, Graessel A, Hellings P, Hoffmann-Sommergruber K, Jutel M, Lau S, Lauerma A, Maria Olaguibel J, O'Mahony L, Ozdemir C, Palomares O, Pfaar O, Sastre J, Scadding G, Schmidt-Weber C, Schmid-Grendelmeier P, Shamji M, Skypala I, Spinola M, Spranger O, Torres M, Vereda A, Bonini S. Prioritizing research challenges and funding for allergy and asthma and the need for translational research-The European Strategic Forum on Allergic Diseases. Allergy. 2019;74(11):2064-76.10.1111/all.13856

Zissler UM, Ulrich M, Jakwerth CA, Rothkirch S, Guerth F, Weckmann M, Schiemann M, Haller B, Schmidt-Weber CB, Chaker AM. Biomatrix for upper and lower airway biomarkers in patients with allergic asthma. J Allergy Clin Immunol. 2018;142(6):1980-3.10.1016/j.jaci.2018.07.027

Zissler UM, Jakwerth CA, Guerth FM, Pechtold L, Aguilar-Pimentel JA, Dietz K, Suttner K, Piontek G, Haller B, Hajdu Z, Schiemann M, Schmidt-Weber CB, Chaker AM. Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AIT. EBioMedicine. 2018;36:475-88.10.1016/j.ebiom.2018.09.016

Schmidt MO, Garman KA, Lee YG, Zuo C, Beck PJ, Tan M, Aguilar-Pimentel JA, Ollert M, Schmidt-Weber C, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Tassi E, Riegel AT, Wellstein A. The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation. J Invest Dermatol. 2018;138(1):179-88.10.1016/j.jid.2017.07.847

Schiener M, Hilger C, Eberlein B, Pascal M, Kuehn A, Revets D, Planchon S, Pietsch G, Serrano P, Moreno-Aguilar C, de la Roca F, Biedermann T, Darsow U, Schmidt-Weber CB, Ollert M, Blank S. The high molecular weight dipeptidyl peptidase IV Pol d 3 is a major allergen of Polistes dominula venom. Sci Rep. 2018;8(1):1318.10.1038/s41598-018-19666-7

Russkamp D, Van Vaerenbergh M, Etzold S, Eberlein B, Darsow U, Schiener M, De Smet L, Absmaier M, Biedermann T, Spillner E, Ollert M, Jakob T, Schmidt-Weber CB, de Graaf DC, Blank S. Characterization of the honeybee venom proteins C1q-like protein and PVF1 and their allergenic potential. Toxicon. 2018;150:198-206.10.1016/j.toxicon.2018.05.017

Rozman J, Rathkolb B, Oestereicher MA, Schütt C, Ravindranath AC, Leuchtenberger S, Sharma S, Kistler M, Willershäuser M, Brommage R, Meehan TF, Mason J, Haselimashhadi H, Hough T, Mallon AM, Wells S, Santos L, Lelliott CJ, White JK, Sorg T, Champy MF, Bower LR, Reynolds CL, Flenniken AM, Murray SA, Nutter LMJ, Svenson KL, West D, Tocchini-Valentini GP, Beaudet AL, Bosch F, Braun RB, Dobbie MS, Gao X, Herault Y, Moshiri A, Moore BA, Kent Lloyd KC, McKerlie C, Masuya H, Tanaka N, Flicek P, Parkinson HE, Sedlacek R, Seong JK, Wang CL, Moore M, Brown SD, Tschöp MH, Wurst W, Klingenspor M, Wolf E, Beckers J, Machicao F, Peter A, Staiger H, Häring HU, Grallert H, Campillos M, Maier H, Fuchs H, Gailus-Durner V, Werner T, Hrabe de Angelis M. Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Nat Commun. 2018;9(1):288.10.1038/s41467-017-01995-2

Roberts G, Pfaar O, Akdis CA, Ansotegui IJ, Durham SR, Gerth van Wijk R, Halken S, Larenas-Linnemann D, Pawankar R, Pitsios C, Sheikh A, Worm M, Arasi S, Calderon MA, Cingi C, Dhami S, Fauquert JL, Hamelmann E, Hellings P, Jacobsen L, Knol EF, Lin SY, Maggina P, Mösges R, Oude Elberink JNG, Pajno GB, Pastorello EA, Penagos M, Rotiroti G, Schmidt-Weber CB, Timmermans F, Tsilochristou O, Varga EM, Wilkinson JN, Williams A, Zhang L, Agache I, Angier E, Fernandez-Rivas M, Jutel M, Lau S, van Ree R, Ryan D, Sturm GJ, Muraro A. EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis. Allergy. 2018;73(4):765-98.10.1111/all.13317

Pfaar O, Bonini S, Cardona V, Demoly P, Jakob T, Jutel M, Kleine-Tebbe J, Klimek L, Klysner S, Kopp MV, Kuna P, Larché M, Muraro A, Schmidt-Weber CB, Shamji MH, Simonsen K, Somoza C, Valovirta E, Zieglmayer P, Zuberbier T, Wahn U. Perspectives in allergen immunotherapy: 2017 and beyond. Allergy. 2018;73 Suppl 104:5-23.10.1111/all.13355

Nikolakopoulou P, Chatzigeorgiou A, Kourtzelis I, Toutouna L, Masjkur J, Arps-Forker C, Poser SW, Rozman J, Rathkolb B, Aguilar-Pimentel JA, Wolf E, Klingenspor M, Ollert M, Schmidt-Weber C, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Tsata V, Monasor LS, Troullinaki M, Witt A, Anastasiou V, Chrousos G, Yi CX, García-Cáceres C, Tschöp MH, Bornstein SR, Androutsellis-Theotokis A. Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain. Sci Rep. 2018;8(1):11335.10.1038/s41598-018-29434-2

Mattii M, Lovászi M, Garzorz N, Atenhan A, Quaranta M, Lauffer F, Konstantinow A, Küpper M, Zouboulis CC, Kemeny L, Eyerich K, Schmidt-Weber CB, Törőcsik D, Eyerich S. Sebocytes contribute to skin inflammation by promoting the differentiation of T helper 17 cells. Br J Dermatol. 2018;178(3):722-30.10.1111/bjd.15879

Lauffer F, Jargosch M, Krause L, Garzorz-Stark N, Franz R, Roenneberg S, Böhner A, Mueller NS, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K. Type I Immune Response Induces Keratinocyte Necroptosis and Is Associated with Interface Dermatitis. J Invest Dermatol. 2018;138(8):1785-94.10.1016/j.jid.2018.02.034

Landgraf-Rauf K, Boeck A, Siemens D, Klucker E, Vogelsang V, Schmidt S, Kunze S, Weissenbacher C, Graessel A, Schmidt-Weber C, von Mutius E, Schedel M, Schaub B. IRF-1 SNPs influence the risk for childhood allergic asthma: A critical role for pro-inflammatory immune regulation. Pediatr Allergy Immunol. 2018;29(1):34-41.10.1111/pai.12821

Klimek L, Kündig T, Kramer MF, Guethoff S, Jensen-Jarolim E, Schmidt-Weber CB, Palomares O, Mohsen MO, Jakob T, Bachmann M. Virus-like particles (VLP) in prophylaxis and immunotherapy of allergic diseases. Allergo J Int. 2018;27(8):245-55.10.1007/s40629-018-0074-y

Garzorz-Stark N, Lauffer F, Krause L, Thomas J, Atenhan A, Franz R, Roenneberg S, Boehner A, Jargosch M, Batra R, Mueller NS, Haak S, Groß C, Groß O, Traidl-Hoffmann C, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K. Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate T(H)17-deviated acute contact dermatitis in human subjects. J Allergy Clin Immunol. 2018;141(4):1320-33.e11.10.1016/j.jaci.2017.07.045

Fuchs H, Aguilar-Pimentel JA, Amarie OV, Becker L, Calzada-Wack J, Cho YL, Garrett L, Hölter SM, Irmler M, Kistler M, Kraiger M, Mayer-Kuckuk P, Moreth K, Rathkolb B, Rozman J, da Silva Buttkus P, Treise I, Zimprich A, Gampe K, Hutterer C, Stöger C, Leuchtenberger S, Maier H, Miller M, Scheideler A, Wu M, Beckers J, Bekeredjian R, Brielmeier M, Busch DH, Klingenspor M, Klopstock T, Ollert M, Schmidt-Weber C, Stöger T, Wolf E, Wurst W, Yildirim A, Zimmer A, Gailus-Durner V, Hrabě de Angelis M. Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic. Behav Brain Res. 2018;352:187-96.10.1016/j.bbr.2017.09.048

Chaker AM, Zissler UM, Poulos N, Wagenmann M, Bas M, Gürth F, Xanthou G, Schmidt-Weber C. Activin-A Is a Pro-Inflammatory Regulator in Type-2-Driven Upper Airway Disease. Int Arch Allergy Immunol. 2018;176(1):15-25.10.1159/000487930

Buters JTM, Antunes C, Galveias A, Bergmann KC, Thibaudon M, Galán C, Schmidt-Weber C, Oteros J. Pollen and spore monitoring in the world. Clin Transl Allergy. 2018;8:9.10.1186/s13601-018-0197-8

Buters J, Schmidt-Weber C, Oteros J. Next-generation pollen monitoring and dissemination. Allergy. 2018;73(10):1944-5.10.1111/all.13585

André V, Gau C, Scheideler A, Aguilar-Pimentel JA, Amarie OV, Becker L, Garrett L, Hans W, Hölter SM, Janik D, Moreth K, Neff F, Östereicher M, Racz I, Rathkolb B, Rozman J, Bekeredjian R, Graw J, Klingenspor M, Klopstock T, Ollert M, Schmidt-Weber C, Wolf E, Wurst W, Gailus-Durner V, Brielmeier M, Fuchs H, Hrabé de Angelis M. Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data. PLoS Biol. 2018;16(4):e2005019.10.1371/journal.pbio.2005019

Xie K, Neff F, Markert A, Rozman J, Aguilar-Pimentel JA, Amarie OV, Becker L, Brommage R, Garrett L, Henzel KS, Hölter SM, Janik D, Lehmann I, Moreth K, Pearson BL, Racz I, Rathkolb B, Ryan DP, Schröder S, Treise I, Bekeredjian R, Busch DH, Graw J, Ehninger G, Klingenspor M, Klopstock T, Ollert M, Sandholzer M, Schmidt-Weber C, Weiergräber M, Wolf E, Wurst W, Zimmer A, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Ehninger D. Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice. Nat Commun. 2017;8(1):155.10.1038/s41467-017-00178-3

Steiert SA, Zissler UM, Chaker AM, Esser-von-Bieren J, Dittlein D, Guerth F, Jakwerth CA, Piontek G, Zahner C, Drewe J, Traidl-Hoffmann C, Schmidt-Weber CB, Gilles S. Anti-inflammatory effects of the petasin phyto drug Ze339 are mediated by inhibition of the STAT pathway. Biofactors. 2017;43(3):388-99.10.1002/biof.1349

Shamji MH, Kappen JH, Akdis M, Jensen-Jarolim E, Knol EF, Kleine-Tebbe J, Bohle B, Chaker AM, Till SJ, Valenta R, Poulsen LK, Calderon MA, Demoly P, Pfaar O, Jacobsen L, Durham SR, Schmidt-Weber CB. Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper. Allergy. 2017;72(8):1156-73.10.1111/all.13138

Schiener M, Graessel A, Ollert M, Schmidt-Weber CB, Blank S. Allergen-specific immunotherapy of Hymenoptera venom allergy - also a matter of diagnosis. Hum Vaccin Immunother. 2017;13(10):2467-81.10.1080/21645515.2017.1334745

Schiener M, Eberlein B, Moreno-Aguilar C, Pietsch G, Serrano P, McIntyre M, Schwarze L, Russkamp D, Biedermann T, Spillner E, Darsow U, Ollert M, Schmidt-Weber CB, Blank S. Application of recombinant antigen 5 allergens from seven allergy-relevant Hymenoptera species in diagnostics. Allergy. 2017;72(1):98-108.10.1111/all.13000

Marzaioli V, Groß CJ, Weichenmeier I, Schmidt-Weber CB, Gutermuth J, Groß O, Alessandrini F. Specific Surface Modifications of Silica Nanoparticles Diminish Inflammasome Activation and In Vivo Expression of Selected Inflammatory Genes. Nanomaterials (Basel). 2017;7(11).10.3390/nano7110355

Klimek L, Schmidt-Weber CB, Kramer MF, Skinner MA, Heath MD. Clinical use of adjuvants in allergen-immunotherapy. Expert Rev Clin Immunol. 2017;13(6):599-610.10.1080/1744666x.2017.1292133

Karp NA, Mason J, Beaudet AL, Benjamini Y, Bower L, Braun RE, Brown SDM, Chesler EJ, Dickinson ME, Flenniken AM, Fuchs H, Angelis MH, Gao X, Guo S, Greenaway S, Heller R, Herault Y, Justice MJ, Kurbatova N, Lelliott CJ, Lloyd KCK, Mallon AM, Mank JE, Masuya H, McKerlie C, Meehan TF, Mott RF, Murray SA, Parkinson H, Ramirez-Solis R, Santos L, Seavitt JR, Smedley D, Sorg T, Speak AO, Steel KP, Svenson KL, Wakana S, West D, Wells S, Westerberg H, Yaacoby S, White JK. Prevalence of sexual dimorphism in mammalian phenotypic traits. Nat Commun. 2017;8:15475.10.1038/ncomms15475

Hellings PW, Akdis CA, Bachert C, Bousquet J, Pugin B, Adriaensen G, Advani R, Agache I, Anjo C, Anmolsingh R, Annoni E, Bieber T, Bizaki A, Braverman I, Callebaut I, Castillo Vizuete JA, Chalermwatanachai T, Chmielewski R, Cingi C, Cools L, Coppije C, Cornet ME, De Boeck I, De Corso E, De Greve G, Doulaptsi M, Edmiston R, Erskine S, Gevaert E, Gevaert P, Golebski K, Hopkins C, Hox V, Jaeggi C, Joos G, Khwaja S, Kjeldsen A, Klimek L, Koennecke M, Kortekaas Krohn I, Krysko O, Kumar BN, Langdon C, Lange B, Lekakis G, Levie P, Lourijsen E, Lund VJ, Martens K, R MS, Mullol J, Nyembue TD, Palkonen S, Philpott C, Pimentel J, Poirrier A, Pratas AC, Prokopakis E, Pujols L, Rombaux P, Schmidt-Weber C, Segboer C, Spacova I, Staikuniene J, Steelant B, Steinsvik EA, Teufelberger A, Van Gerven L, Van Gool K, Verbrugge R, Verhaeghe B, Virkkula P, Vlaminck S, Vries-Uss E, Wagenmann M, Zuberbier T, Seys SF, Fokkens WJ. EUFOREA Rhinology Research Forum 2016: report of the brainstorming sessions on needs and priorities in rhinitis and rhinosinusitis. Rhinology. 2017;55(3):202-10.10.4193/Rhin17.028

Gargaro M, Epifano F, Fiorito S, Taddeo VA, Genovese S, Pirro M, Turco A, Puccetti P, Schmidt-Weber CB, Fallarino F. Interaction of 7-Alkoxycoumarins with the Aryl Hydrocarbon Receptor. J Nat Prod. 2017;80(6):1939-43.10.1021/acs.jnatprod.7b00173

Eyerich S, Traidl-Hoffmann C, Behrendt H, Cavani A, Schmidt-Weber CB, Ring J, Eyerich K. Novel key cytokines in allergy: IL-17, IL-22. Allergol Select. 2017;1(1):71-6.10.5414/alx01403e

Egaña I, Kaito H, Nitzsche A, Becker L, Ballester-Lopez C, Niaudet C, Petkova M, Liu W, Vanlandewijck M, Vernaleken A, Klopstock T, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Rask-Andersen H, Johansson HJ, Lehtiö J, He L, Yildirim A, Hellström M. Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema. Sci Rep. 2017;7(1):15453.10.1038/s41598-017-14894-9

Effner R, Hiller J, Eyerich S, Traidl-Hoffmann C, Brockow K, Triggiani M, Behrendt H, Schmidt-Weber CB, Buters JT. Cytochrome P450s in human immune cells regulate IL-22 and c-Kit via an AHR feedback loop. Sci Rep. 2017;7:44005.10.1038/srep44005

Dietz K, de Los Reyes Jiménez M, Gollwitzer ES, Chaker AM, Zissler UM, Rådmark OP, Baarsma HA, Königshoff M, Schmidt-Weber CB, Marsland BJ, Esser-von Bieren J. Age dictates a steroid-resistant cascade of Wnt5a, transglutaminase 2, and leukotrienes in inflamed airways. J Allergy Clin Immunol. 2017;139(4):1343-54.e6.10.1016/j.jaci.2016.07.014

Dhami S, Nurmatov U, Arasi S, Khan T, Asaria M, Zaman H, Agarwal A, Netuveli G, Roberts G, Pfaar O, Muraro A, Ansotegui IJ, Calderon M, Cingi C, Durham S, van Wijk RG, Halken S, Hamelmann E, Hellings P, Jacobsen L, Knol E, Larenas-Linnemann D, Lin S, Maggina P, Mösges R, Oude Elberink H, Pajno G, Panwankar R, Pastorello E, Penagos M, Pitsios C, Rotiroti G, Timmermans F, Tsilochristou O, Varga EM, Schmidt-Weber C, Wilkinson J, Williams A, Worm M, Zhang L, Sheikh A. Allergen immunotherapy for allergic rhinoconjunctivitis: A systematic review and meta-analysis. Allergy. 2017;72(11):1597-631.10.1111/all.13201

Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Erratum to: Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2017;7:32.10.1186/s13601-017-0167-6

Chaker AM, Zissler UM, Wagenmann M, Schmidt-Weber C. Biomarkers in Allergic Airway Disease: Simply Complex. ORL J Otorhinolaryngol Relat Spec. 2017;79(1-2):72-7.10.1159/000455725

Bowl MR, Simon MM, Ingham NJ, Greenaway S, Santos L, Cater H, Taylor S, Mason J, Kurbatova N, Pearson S, Bower LR, Clary DA, Meziane H, Reilly P, Minowa O, Kelsey L, Tocchini-Valentini GP, Gao X, Bradley A, Skarnes WC, Moore M, Beaudet AL, Justice MJ, Seavitt J, Dickinson ME, Wurst W, de Angelis MH, Herault Y, Wakana S, Nutter LMJ, Flenniken AM, McKerlie C, Murray SA, Svenson KL, Braun RE, West DB, Lloyd KCK, Adams DJ, White J, Karp N, Flicek P, Smedley D, Meehan TF, Parkinson HE, Teboul LM, Wells S, Steel KP, Mallon AM, Brown SDM. A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Nat Commun. 2017;8(1):886.10.1038/s41467-017-00595-4

Blank S, Etzold S, Darsow U, Schiener M, Eberlein B, Russkamp D, Wolf S, Graessel A, Biedermann T, Ollert M, Schmidt-Weber CB. Component-resolved evaluation of the content of major allergens in therapeutic extracts for specific immunotherapy of honeybee venom allergy. Hum Vaccin Immunother. 2017;13(10):2482-9.10.1080/21645515.2017.1323603

Alessandrini F, Vennemann A, Gschwendtner S, Neumann AU, Rothballer M, Seher T, Wimmer M, Kublik S, Traidl-Hoffmann C, Schloter M, Wiemann M, Schmidt-Weber CB. Pro-Inflammatory versus Immunomodulatory Effects of Silver Nanoparticles in the Lung: The Critical Role of Dose, Size and Surface Modification. Nanomaterials (Basel). 2017;7(10).10.3390/nano7100300

Aguilar-Pimentel A, Graessel A, Alessandrini F, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Russkamp D, Chaker A, Ollert M, Blank S, Gutermuth J, Schmidt-Weber CB. Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma. PLoS One. 2017;12(6):e0178563.10.1371/journal.pone.0178563

Krause L, Mourantchanian V, Brockow K, Theis FJ, Schmidt-Weber CB, Knapp B, Mueller NS, Eyerich S. A computational model to predict severity of atopic eczema from 30 serum proteins. J Allergy Clin Immunol. 2016;138(4):1207-10.e2.10.1016/j.jaci.2016.04.018

Gilles-Stein S, Beck I, Chaker A, Bas M, McIntyre M, Cifuentes L, Petersen A, Gutermuth J, Schmidt-Weber C, Behrendt H, Traidl-Hoffmann C. Pollen derived low molecular compounds enhance the human allergen specific immune response in vivo. Clin Exp Allergy. 2016;46(10):1355-65.10.1111/cea.12739

Garzorz-Stark N, Krause L, Lauffer F, Atenhan A, Thomas J, Stark SP, Franz R, Weidinger S, Balato A, Mueller NS, Theis FJ, Ring J, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K. A novel molecular disease classifier for psoriasis and eczema. Exp Dermatol. 2016;25(10):767-74.10.1111/exd.13077