New video on mechanisms of allergen specific immunotherapy: Exhaustion?

Is exhaustion another mechanism of allergen specific immunotherapy? Have a look for this video & open access paper: An exhausted phenotype of TH2 cells is primed by allergen...https://youtu.be/ktECcpaecqs OR https://youtu.be/sBHcZR8KdGQ via @YouTube

Quick video: An exhausted phenotype of TH2 cells is primed by allergen exposure, but not reinforced by allergen-specific immunotherapy